W E Biddison
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Explore the profile of W E Biddison including associated specialties, affiliations and a list of published articles.
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Articles
136
Citations
3679
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Recent Articles
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Biddison W, Lichtenfels R, Adibzadeh M, Martin R
Curr Protoc Immunol
. 2008 Apr;
Chapter 7:Unit 7.17.
PMID: 18432831
Measurement of in vitro cytotoxic function of human T cells can be accomplished by polyclonal stimulation of T cell effectors using anti-CD3 antibody, which stimulates all cytolytic effector cells, or...
3.
Biddison W, Martin R
Curr Protoc Immunol
. 2008 Apr;
Appendix 1:Appendix 1I.
PMID: 18432645
This overview discusses the use of peptide-binding motifs to predict interaction with a specific MHC class I or II allele, and gives examples for the use of MHC binding motifs...
4.
Biddison W
Curr Protoc Cell Biol
. 2008 Jan;
Chapter 2:Unit 2.4.
PMID: 18228349
Primary cultures of cells tend to have a limited life span, which in turn limits the availability of a consistent population of cells to study. In this unit, Epstein-Barr virus...
5.
Biddison W
Curr Protoc Cell Biol
. 2008 Jan;
Chapter 2:Unit 2.2.
PMID: 18228347
This unit presents protocols for preparation of lymphocytes from peripheral (whole) blood or leucopherisis samples, first by differential centrifugation in Ficoll-Hypaque to separate them from erythrocytes and granulocytes. Repeated centrifugation...
6.
Whitney L, Ludwin S, McFarland H, Biddison W
J Neuroimmunol
. 2001 Dec;
121(1-2):40-8.
PMID: 11730938
Multiple sclerosis (MS) is a demyelinating disease of the central nervous system characterized by lesions that are areas of blood-brain barrier breakdown, inflammation and myelin damage. To identify genes that...
7.
Zhao Y, Gran B, Pinilla C, Markovic-Plese S, Hemmer B, Tzou A, et al.
J Immunol
. 2001 Aug;
167(4):2130-41.
PMID: 11489997
The interaction of TCRs with MHC peptide ligands can be highly flexible, so that many different peptides are recognized by the same TCR in the context of a single restriction...
8.
Baker B, Turner R, Gagnon S, Wiley D, Biddison W
J Exp Med
. 2001 Mar;
193(5):551-62.
PMID: 11238586
Structural studies have shown that class I major histocompatibility complex (MHC)-restricted peptide-specific T cell receptor (TCR)-alpha/betas make multiple contacts with the alpha1 and alpha2 helices of the MHC, but it...
9.
Baker B, Ding Y, Garboczi D, Biddison W, Wiley D
Cold Spring Harb Symp Quant Biol
. 2001 Mar;
64:235-41.
PMID: 11232291
No abstract available.
10.
Baker B, Gagnon S, Biddison W, Wiley D
Immunity
. 2000 Nov;
13(4):475-84.
PMID: 11070166
The structure of the A6 alphabetaTCR/HTLV-1 Tax-peptide/MHC I complex with proline 6 of Tax substituted with alanine (P6A), an antagonist, is nearly identical to the structure with wild-type Tax agonist....