W D Cress
Overview
Explore the profile of W D Cress including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
1516
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Recent Articles
1.
Engel B, Cress W, Santiago-Cardona P
Cell Health Cytoskelet
. 2017 Jan;
7:1-10.
PMID: 28090172
was the first tumor suppressor gene discovered. Over four decades of work have revealed that the Rb protein (pRb) is a master regulator of biological pathways influencing virtually every aspect...
2.
Schabath M, Welsh E, Fulp W, Chen L, Teer J, Thompson Z, et al.
Oncogene
. 2015 Oct;
35(24):3209-16.
PMID: 26477306
While mutations in the KRAS oncogene are among the most prevalent in human cancer, there are few successful treatments to target these tumors. It is also likely that heterogeneity in...
3.
Engel B, Welsh E, Emmons M, Santiago-Cardona P, Cress W
Cell Death Dis
. 2013 Nov;
4:e938.
PMID: 24287699
pRb is known as a classic cell cycle regulator whose inactivation is an important initiator of tumorigenesis. However, more recently, it has also been linked to tumor progression. This study...
4.
Ma Y, Cress W
Oncogene
. 2006 Dec;
26(24):3532-40.
PMID: 17173074
In spite of the fact that cyclin-dependent kinase (cdk) inhibiting drugs are potent transcriptional repressors, we discover that p57 (Kip2, CDKN1C) transcription is significantly upregulated by three small molecule cdk...
5.
Frame F, Rogoff H, Pickering M, Cress W, Kowalik T
Oncogene
. 2006 Jan;
25(23):3258-66.
PMID: 16434972
Deregulation of the Rb/E2F pathway in human fibroblasts results in an E2F1-mediated apoptosis dependent on Atm, Nbs1, Chk2 and p53. Here, we show that E2F1 expression results in MRN foci...
6.
Cuenca A, Cress W, GOOD R, Marikar Y, Engelman R
Exp Biol Med (Maywood)
. 2001 Dec;
226(11):1061-7.
PMID: 11743143
Calorie restriction without essential nutrient deficiency (calorie restriction, CR) abrogates experimental carcinogenesis and extends healthful life span. To test whether CR influences cell-cycle protein expression during the hepatocellular proliferation induced...
7.
Hu X, Cress W, Zhong Q, Zuckerman K
Biochem Biophys Res Commun
. 2000 Oct;
276(3):930-9.
PMID: 11027571
Transforming growth factor beta (TGFbeta)1 induced dephosphorylation of pRb at multiple serine and threonine residues including Ser249/Thr252, Thr373, Ser780, and Ser807/811 in MV4-11 cells. Likewise, TGFbeta1 caused the dephosphorylation of...
8.
Wharton W, Savell J, Cress W, Seto E, Pledger W
J Biol Chem
. 2000 Aug;
275(43):33981-7.
PMID: 10945992
Trichostatin A (TSA), a global repressor of histone deacetylase activity, inhibits the proliferation of a number of cell types. However, the identification of the mechanisms underlying TSA-mediated growth arrests has...
9.
He Y, Armanious M, Thomas M, Cress W
Oncogene
. 2000 Aug;
19(30):3422-33.
PMID: 10918599
We have identified a novel form of the full-length E2F-3 protein that we term E2F-3B. In contrast to full-length E2F-3, which is expressed only at the G1/S boundary, E2F-3B is...
10.
Zhang X, Wharton W, Donovan M, Coppola D, Croxton R, Cress W, et al.
Mol Biol Cell
. 2000 Jun;
11(6):2117-30.
PMID: 10848633
The cyclin/cyclin-dependent kinase (cdk) inhibitor p27(kip1) is thought to be responsible for the onset and maintenance of the quiescent state. It is possible, however, that cells respond differently to p27(kip1)...