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Volker Ullrich

Explore the profile of Volker Ullrich including associated specialties, affiliations and a list of published articles. Areas
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Articles 44
Citations 1076
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Recent Articles
1.
Schildknecht S, von Kriegsheim A, Vujacic-Mirski K, Di Lisa F, Ullrich V, Daiber A
Redox Biol . 2022 Aug; 56:102439. PMID: 35995009
Nitrosation of critical thiols has been elaborated as reversible posttranslational modification with regulatory function in multiple disorders. Reversibility of S-nitrosation is generally associated with enzyme-mediated one-electron reductions, catalyzed by the...
2.
Mikhed Y, Bruns K, Schildknecht S, Jorg M, Dib M, Oelze M, et al.
Redox Biol . 2015 Dec; 7:39-47. PMID: 26629950
There has been some dispute regarding reaction products formed at physiological peroxynitrite fluxes in the nanomolar range with phenolic molecules, when used to predict the behavior of protein-bound aromatic amino...
3.
Riplinger C, Bill E, Daiber A, Ullrich V, Shoun H, Neese F
Chemistry . 2014 Jan; 20(6):1602-14. PMID: 24453075
Cytochrome P450 NO reductase is an unusual member of the cytochrome P450 superfamily. It catalyzes the reduction of nitric oxide to nitrous oxide. The reaction intermediates were studied in detail...
4.
Muller N, Moreno-Villanueva M, Fischbach A, Kienhofer J, Martello R, Dedon P, et al.
Toxicology . 2013 May; 310:15-21. PMID: 23707620
The oxidation of guanine to 8-oxo-2'-deoxyguanosine (8-oxo-dG) is one of the most abundant and best studied oxidative DNA lesions and is commonly used as a biomarker for oxidative stress. Over...
5.
Daiber A, Daub S, Bachschmid M, Schildknecht S, Oelze M, Steven S, et al.
Int J Mol Sci . 2013 Apr; 14(4):7542-70. PMID: 23567270
The reaction product of nitric oxide and superoxide, peroxynitrite, is a potent biological oxidant. The most important oxidative protein modifications described for peroxynitrite are cysteine-thiol oxidation and tyrosine nitration. We...
6.
Ullrich V, Schildknecht S
Antioxid Redox Signal . 2012 Jul; 20(2):325-38. PMID: 22793377
Significance: Sudden hypoxia requires a rapid response in tissues with high energy demand. Mitochondria are rapid sensors for a lack of oxygen, but no consistent mechanism for the sensing process...
7.
Schildknecht S, Karreman C, Daiber A, Zhao C, Hamacher J, Perlman D, et al.
Antioxid Redox Signal . 2012 May; 17(10):1393-406. PMID: 22578329
Aims: Prostaglandin endoperoxide H(2) synthase (PGHS) is a well-known target for peroxynitrite-mediated nitration. In several experimental macrophage models, however, the relatively late onset of nitration failed to coincide with the...
8.
Daiber A, Schildknecht S, Muller J, Kamuf J, Bachschmid M, Ullrich V
Free Radic Biol Med . 2009 May; 47(4):458-67. PMID: 19477267
S-nitros(yl)ation belongs to the redox-based posttranslational modifications of proteins but the underlying chemistry is controversial. In contrast to current concepts involving the autoxidation of nitric oxide ((.)NO, nitrogen monoxide), we...
9.
Kienhofer J, Haussler D, Ruckelshausen F, Muessig E, Weber K, Pimentel D, et al.
FASEB J . 2009 Feb; 23(7):2034-44. PMID: 19228881
Mitochondrial DNA (mtDNA) is organized in protein-DNA macrocomplexes called nucleoids. Average nucleoids contain 2-8 mtDNA molecules, which are organized by the histone-like mitochondrial transcription factor A. Besides well-characterized constituents, such...
10.
Schildknecht S, Ullrich V
Arch Biochem Biophys . 2008 Nov; 484(2):183-9. PMID: 18983814
Prostanoids and nitric oxide ((.)NO) are essential modulators of cardiovascular function in health and disease. Among the (.)NO-derived species formed in cells, peroxynitrite (ONOO(-)) is generally associated with its role...