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Volker Assmann

Explore the profile of Volker Assmann including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Bartkowiak K, Kwiatkowski M, Buck F, Gorges T, Nilse L, Assmann V, et al.
Cancer Res . 2015 Nov; 75(24):5367-77. PMID: 26573792
Disseminated tumor cells (DTC), which share mesenchymal and epithelial properties, are considered to be metastasis-initiating cells in breast cancer. However, the mechanisms supporting DTC survival are poorly understood. DTC extravasation...
2.
Riethdorf S, Frey S, Santjer S, Stoupiec M, Otto B, Riethdorf L, et al.
Int J Cancer . 2015 Sep; 138(4):949-63. PMID: 26355710
The transcription factor grainyhead-like 2 (GRHL2) plays a crucial role in various developmental processes. Although GRHL2 recently has attracted considerable interest in that it could be identified as a novel...
3.
Werner S, Frey S, Riethdorf S, Schulze C, Alawi M, Kling L, et al.
J Biol Chem . 2013 Jul; 288(32):22993-3008. PMID: 23814079
Using a retrovirus-mediated cDNA expression cloning approach, we identified the grainyhead-like 2 (GRHL2) transcription factor as novel protooncogene. Overexpression of GRHL2 in NIH3T3 cells induced striking morphological changes, an increase...
4.
Maxwell C, Benitez J, Gomez-Baldo L, Osorio A, Bonifaci N, Fernandez-Ramires R, et al.
PLoS Biol . 2011 Nov; 9(11):e1001199. PMID: 22110403
Differentiated mammary epithelium shows apicobasal polarity, and loss of tissue organization is an early hallmark of breast carcinogenesis. In BRCA1 mutation carriers, accumulation of stem and progenitor cells in normal...
5.
Hein S, Muller V, Kohler N, Wikman H, Krenkel S, Streichert T, et al.
Breast Cancer Res Treat . 2010 Oct; 129(2):347-60. PMID: 20972617
The activated leukocyte cell adhesion molecule (ALCAM) is overexpressed in many mammary tumors, but controversial results about its role and prognostic impact in breast cancer have been reported. Therefore, we...
6.
Pujana M, Han J, Starita L, Stevens K, Tewari M, Ahn J, et al.
Nat Genet . 2007 Oct; 39(11):1338-49. PMID: 17922014
Many cancer-associated genes remain to be identified to clarify the underlying molecular mechanisms of cancer susceptibility and progression. Better understanding is also required of how mutations in cancer genes affect...
7.
Riethdorf S, Reimers N, Assmann V, Kornfeld J, Terracciano L, Sauter G, et al.
Int J Cancer . 2006 May; 119(8):1800-10. PMID: 16721788
Extracellular matrix metalloproteinase inducer expressed by tumor cells stimulates peritumoral fibroblasts to produce matrix metalloproteinases, thus contributing to tumor invasion and metastasis. To assess its suitability as potential therapeutic target,...
8.
Willipinski-Stapelfeldt B, Riethdorf S, Assmann V, Woelfle U, Rau T, Sauter G, et al.
Clin Cancer Res . 2005 Nov; 11(22):8006-14. PMID: 16299229
Purpose: The bone marrow is a frequent and clinically important homing site for early disseminated breast cancer cells. Here, we aimed to profile the protein expression of these cells using...
9.
Reimers N, Zafrakas K, Assmann V, Egen C, Riethdorf L, Riethdorf S, et al.
Clin Cancer Res . 2004 May; 10(10):3422-8. PMID: 15161697
Purpose: EMMPRIN (extracellular matrix metalloprotease inducer) is a glycosylated member of the immunoglobulin superfamily known to stimulate the production of matrix metalloproteases (MMPs) 1, 2, and 3 and MT1-MMP in...
10.
Stojkovic M, Krebs O, Kolle S, Prelle K, Assmann V, Zakhartchenko V, et al.
Biol Reprod . 2002 Dec; 68(1):60-6. PMID: 12493696
Hyaluronan or hyaluronic acid (HA) is a normal component of mammalian follicular, oviduct, and uterine fluids. Granulosa and expanding cumulus cells secrete large amounts of HA, and when HA is...