Vladimir V Rymar
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Explore the profile of Vladimir V Rymar including associated specialties, affiliations and a list of published articles.
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20
Citations
735
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Recent Articles
1.
Gauthier-Lafreniere E, Aljassar M, Rymar V, Milton J, Sadikot A
Front Neuroinform
. 2022 Aug;
16:878279.
PMID: 35991289
Background: Ordinal scales based on qualitative observation are the mainstay in the clinical assessment of tremor, but are limited by inter-rater reliability, measurement precision, range, and ceiling effects. Quantitative tremor...
2.
Lo P, Rymar V, Kennedy T, Sadikot A
J Neurochem
. 2022 Feb;
161(3):254-265.
PMID: 35118677
Mechanisms that determine the survival of midbrain dopaminergic (mDA) neurons in the adult central nervous system (CNS) are not fully understood. Netrins are a family of secreted proteins that are...
3.
Crevier-Sorbo G, Rymar V, Crevier-Sorbo R, Sadikot A
Acta Neuropathol Commun
. 2020 Feb;
8(1):14.
PMID: 32033588
Huntington's disease (HD) is an autosomal dominant trinucleotide repeat disorder characterized by choreiform movements, dystonia and striatal neuronal loss. Amongst multiple cellular processes, abnormal neurotransmitter signalling and decreased trophic support...
4.
Robertson R, Conte T, Dicaire M, Rymar V, Sadikot A, Bryson-Richardson R, et al.
Am J Pathol
. 2020 Jan;
190(3):554-562.
PMID: 31953038
BCL-2-associated athanogene 3 (BAG3) is a co-chaperone to heat shock proteins important in degrading misfolded proteins through chaperone-assisted selective autophagy. The recurrent dominant BAG3-P209L mutation results in a severe childhood-onset...
5.
Hassani O, Rymar V, Nguyen K, Huo L, Cloutier J, Miller F, et al.
Neurobiol Aging
. 2019 Nov;
85:22-37.
PMID: 31734438
The cause of midbrain dopaminergic (mDA) neuron loss in sporadic Parkinson's disease (PD) is multifactorial, involving cell autonomous factors, cell-cell interactions, and the effects of environmental toxins. Early loss of...
6.
Nguyen K, Rymar V, Sadikot A
Front Cell Neurosci
. 2016 Mar;
10:37.
PMID: 27013968
The principal projection neurons of the striatum are critically dependent on an afferent supply of brain derived neurotrophic factor (BDNF) for neurotrophic support. These neurons express TrkB, the cognate receptor...
7.
Luk K, Rymar V, van den Munckhof P, Nicolau S, Steriade C, Bifsha P, et al.
J Neurochem
. 2013 Jan;
125(6):932-43.
PMID: 23331067
The homeodomain transcription factor Pitx3 is critical for the survival of midbrain dopaminergic (mDA) neurons. Pitx3-deficient mice exhibit severe but selective developmental loss of mDA neurons, with accompanying locomotor deficits...
8.
Fortin G, Bourque M, Mendez J, Leo D, Nordenankar K, Birgner C, et al.
J Neurosci
. 2012 Dec;
32(48):17477-91.
PMID: 23197738
Recent studies have proposed that glutamate corelease by mesostriatal dopamine (DA) neurons regulates behavioral activation by psychostimulants. How and when glutamate release by DA neurons might play this role remains...
9.
Sadikot A, Chakravarty M, Bertrand G, Rymar V, Al-Subaie F, Collins D
Front Syst Neurosci
. 2011 Sep;
5:71.
PMID: 21922002
Functional brain imaging and neurosurgery in subcortical areas often requires visualization of brain nuclei beyond the resolution of current magnetic resonance imaging (MRI) methods. We present techniques used to create:...
10.
Sadikot A, Rymar V
Brain Res Bull
. 2008 Oct;
78(2-3):122-30.
PMID: 18957319
In addition to the cerebral cortex, the striatum receives excitatory input from the thalamus. The centromedian (centre median, CM) and parafascicular (Pf) nuclei are an important source of thalamostriatal projections....