Vladimir A Korshun
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Explore the profile of Vladimir A Korshun including associated specialties, affiliations and a list of published articles.
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88
Citations
523
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Recent Articles
11.
Mikhnovets I, Holoubek J, Panina I, Kotoucek J, Gvozdev D, Chumakov S, et al.
Int J Mol Sci
. 2023 Nov;
24(22).
PMID: 38003673
Amphipathic perylene derivatives are broad-spectrum antivirals against enveloped viruses that act as fusion inhibitors in a light-dependent manner. The compounds target the lipid bilayer of the viral envelope using the...
12.
Mariewskaya K, Gvozdev D, Chistov A, Strakova P, Huvarova I, Svoboda P, et al.
Molecules
. 2023 Sep;
28(17).
PMID: 37687107
Perylenylethynyl derivatives have been recognized as broad-spectrum antivirals that target the lipid envelope of enveloped viruses. In this study, we present novel perylenylethynylphenols that exhibit nanomolar or submicromolar antiviral activity...
13.
Baranova A, Tyurin A, Korshun V, Alferova V
Antibiotics (Basel)
. 2023 Aug;
12(8).
PMID: 37627760
Sensing of antibiotic-bacteria interactions is an important area of research that has gained significant attention in recent years. Antibiotic resistance is a major public health concern, and it is essential...
14.
Kamzeeva P, Aralov A, Alferova V, Korshun V
Curr Issues Mol Biol
. 2023 Aug;
45(8):6851-6879.
PMID: 37623252
The search for new drugs has been greatly accelerated by the emergence of new viruses and drug-resistant strains of known pathogens. Nucleoside analogues (NAs) are a prospective class of antivirals...
15.
Strakova P, Bednar P, Kotoucek J, Holoubek J, Fortova A, Svoboda P, et al.
Virus Res
. 2023 Jun;
334:199158.
PMID: 37339718
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has prompted great interest in novel broad-spectrum antivirals, including perylene-related compounds. In the present study,...
16.
Baranova A, Alferova V, Korshun V, Tyurin A
Life (Basel)
. 2023 May;
13(5).
PMID: 37240718
Natural scaffolds remain an important basis for drug development. Therefore, approaches to natural bioactive compound discovery attract significant attention. In this account, we summarize modern and emerging trends in the...
17.
Sapozhnikova K, Gulyak E, Brylev V, Misyurin V, Oreshkov S, Alexeeva A, et al.
Int J Mol Sci
. 2023 Mar;
24(6).
PMID: 36982208
A universal approach to the construction of antibody-drug conjugates (ADCs) has been developed. It relies on periodate oxidation of naturally present glycans of immunoglobulin G, followed by oxime ligation and,...
18.
Sapozhnikova K, Gulyak E, Misyurin V, Simonova M, Ryabukhina E, Alexeeva A, et al.
Molecules
. 2023 Jan;
28(1).
PMID: 36615611
Fluorescent antibodies have proved to be an invaluable tool for molecular biology and diagnostics. They are routinely produced by modification of lysine residues, which leads to high heterogeneity. As such,...
19.
Ilin V, Pyzhik E, Balakhonov A, Kiryushin M, Shcherbatova E, Kuznetsov A, et al.
Molecules
. 2023 Jan;
28(1).
PMID: 36615487
Central nervous system tumors related to gliomas are of neuroectodermal origin and cover about 30% of all primary brain tumors. Glioma is not susceptible to any therapy and surgical attack...
20.
Mariewskaya K, Krasilnikov M, Korshun V, Ustinov A, Alferova V
Int J Mol Sci
. 2023 Jan;
24(1).
PMID: 36613629
Broad antiviral activity in vitro is known for many organic photosensitizers generating reactive oxygen species under irradiation with visible light. Low tissue penetration of visible light prevents further development of...