Vladimir A Korshun
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Explore the profile of Vladimir A Korshun including associated specialties, affiliations and a list of published articles.
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88
Citations
523
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Recent Articles
1.
Krasilnikov M, Mazur R, Chumakov S, Denisov V, Goldenderg E, Nikolaenko Y, et al.
Chembiochem
. 2025 Mar;
:e202401019.
PMID: 40042395
The development of broad-spectrum antiviral drugs effective against a wide variety of viruses is of significant practical importance. Derivatives of perylene, a pentacyclic aromatic hydrocarbon, demonstrate pronounced antiviral activity. These...
2.
Kamzeeva P, Alferova V, Korshun V, Varizhuk A, Aralov A
Int J Mol Sci
. 2025 Feb;
26(3).
PMID: 39940956
RNA G-quadruplexes (rG4s) in 5'-UTRs represent complex regulatory elements capable of both inhibiting and activating mRNA translation through diverse mechanisms in eukaryotes. This review analyzes the evolution of our understanding...
3.
Gulyak E, Brylev V, Zhitlov M, Komarova O, Ustinov A, Sapozhnikova K, et al.
Molecules
. 2025 Jan;
30(1.
PMID: 39795114
Sulfonated indocyanines 3 and 5 (sCy3, sCy5) are widely used to label biomolecules. Their high molar absorption coefficients and lack of spectral overlap with biopolymers make them ideal as linker...
4.
Maryewski X, Krasilnikov M, Strakova P, Holoubek J, Frckova T, Panina I, et al.
ACS Appl Mater Interfaces
. 2025 Jan;
17(3):4502-4528.
PMID: 39772406
Enveloped viruses, such as flaviviruses and coronaviruses, are pathogens of significant medical concern that cause severe infections in humans. Some photosensitizers are known to possess virucidal activity against enveloped viruses,...
5.
Gulyak E, Komarova O, Prokopenko Y, Faizullina E, Malabuiok D, Ibragimova A, et al.
Int J Mol Sci
. 2025 Jan;
25(24.
PMID: 39769122
Homogeneous antibody-drug conjugates (ADCs) exhibit significantly improved pharmacological properties compared to their heterogeneous counterparts. Site-specific conjugation of the payload to the IgG required for homogeneity can be achieved using enzymes....
6.
Alferova V, Baranova A, Belozerova O, Gulyak E, Mikhaylov A, Solovev Y, et al.
Antibiotics (Basel)
. 2025 Jan;
13(12.
PMID: 39766557
Irumamycin (Iru) is a complex polyketide with pronounced antifungal activity produced by a type I polyketide (PKS) synthase. Iru features a unique hemiketal ring and an epoxide group, making its...
7.
Brylev V, Ryabukhina E, Nazarova E, Samoylenkova N, Gulyak E, Sapozhnikova K, et al.
Pharmaceutics
. 2024 Nov;
16(11).
PMID: 39598559
Targeted delivery of chemotherapeutic agents is a well-established approach to cancer therapy. Antibody-drug conjugates (ADCs) typically carry toxic payloads attached to a tumor-associated antigen-targeting IgG antibody via an enzyme-cleavable linker...
8.
Baranova A, Alferova V, Korshun V, Tyurin A
Biotechnol Appl Biochem
. 2024 Oct;
PMID: 39467068
In this review, we aim to summarize experimental data and approaches to identifying cellular targets or mechanisms of action of antibacterials based on imaging techniques. Imaging-based profiling methods, such as...
9.
Kravchenko T, Paramonov A, Kudzhaev A, Efimova S, Khorev A, Kudryakova G, et al.
J Nat Prod
. 2024 Feb;
87(4):664-674.
PMID: 38362867
We report the molecular mechanism of action of gausemycins and the isolation of new members of the family, gausemycins C (), D (), E (), and F (), the minor...
10.
Gulyak E, Alferova V, Korshun V, Sapozhnikova K
Molecules
. 2023 Dec;
28(23).
PMID: 38067618
Antibodies and their derivatives (scFv, Fabs, etc.) represent a unique class of biomolecules that combine selectivity with the ability to target drug delivery. Currently, one of the most promising endeavors...