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Vivian H Gersuk

Explore the profile of Vivian H Gersuk including associated specialties, affiliations and a list of published articles. Areas
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Articles 28
Citations 1003
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Recent Articles
1.
Malueg M, Moo K, Arnett A, Edwards T, Ruskin S, Lambert K, et al.
Immunohorizons . 2025 Jan; 9(1). PMID: 39846842
Dysregulated differentiation of naïve CD4+ T cells into T helper 17 (Th17) cells is likely a key factor predisposing to many autoimmune diseases. Therefore, better understanding how Th17 differentiation is...
2.
Witkop E, Diggins K, Wiedeman A, Serti E, Nepom G, Gersuk V, et al.
Commun Biol . 2024 Jun; 7(1):773. PMID: 38937521
Distinct Natural Killer (NK)-like CD57 and PD-1 CD8 exhausted-like T cell populations (Tex) have both been linked to beneficial immunotherapy response in autoimmune type 1 diabetes (T1D) patients. The origins...
3.
Morrell E, Holton S, Lawrance M, Orlov M, Franklin Z, Mitchem M, et al.
Nat Commun . 2023 Nov; 14(1):7443. PMID: 37978185
The transcriptional and phenotypic characteristics that define alveolar monocyte and macrophage subsets in acute hypoxemic respiratory failure (AHRF) are poorly understood. Here, we apply CITE-seq (single-cell RNA-sequencing and cell-surface protein...
4.
Balmas E, Chen J, Hu A, DeBerg H, Rosasco M, Gersuk V, et al.
JCI Insight . 2023 Sep; 8(21. PMID: 37751304
Variation in the preservation of β cell function in clinical trials in type 1 diabetes (T1D) has emphasized the need to define biomarkers to predict treatment response. The T1DAL trial...
5.
Jacobsen L, Diggins K, Blanchfield L, McNichols J, Perry D, Brant J, et al.
JCI Insight . 2023 Jul; 8(16). PMID: 37432736
BACKGROUNDLow-dose anti-thymocyte globulin (ATG) transiently preserves C-peptide and lowers HbA1c in individuals with recent-onset type 1 diabetes (T1D); however, the mechanisms of action and features of the response remain unclear....
6.
Bolouri H, Ries R, Wiedeman A, Hylkema T, Scheiding S, Gersuk V, et al.
Nat Commun . 2022 Nov; 13(1):7186. PMID: 36418348
High levels of the inflammatory cytokine IL-6 in the bone marrow are associated with poor outcomes in pediatric acute myeloid leukemia (pAML), but its etiology remains unknown. Using RNA-seq data...
7.
Lukaszewski R, Jones H, Gersuk V, Russell P, Simpson A, Brealey D, et al.
Intensive Care Med . 2022 Jul; 48(9):1133-1143. PMID: 35831640
Purpose: Early accurate diagnosis of infection ± organ dysfunction (sepsis) remains a major challenge in clinical practice. Utilizing effective biomarkers to identify infection and impending organ dysfunction before the onset...
8.
Bajzik V, DeBerg H, Garabatos N, Rust B, Obrien K, Nguyen Q, et al.
Allergy . 2022 Mar; 77(8):2534-2548. PMID: 35266148
Background: The PALISADE study, an international, phase 3 trial of peanut oral immunotherapy (POIT) with AR101, resulted in desensitization in children and adolescents who were highly allergic to peanut. An...
9.
Lambert K, Moo K, Arnett A, Goel G, Hu A, Flynn K, et al.
Sci Transl Med . 2022 Jan; 14(627):eabi4888. PMID: 35020411
Individuals with Down syndrome show cellular and clinical features of dysregulated aging of the immune system, including a shift from naïve to memory T cells and increased incidence of autoimmunity....
10.
Smithmyer M, Wiedeman A, Skibinski D, Savage A, Acosta-Vega C, Scheiding S, et al.
Cytometry A . 2021 Dec; 101(4):351-360. PMID: 34967113
Mislabeling samples or data with the wrong participant information can affect study integrity and lead investigators to draw inaccurate conclusions. Quality control to prevent these types of errors is commonly...