Vivek Das
Overview
Explore the profile of Vivek Das including associated specialties, affiliations and a list of published articles.
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14
Citations
206
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Recent Articles
1.
Alakwaa F, Das V, Majumdar A, Nair V, Fermin D, Dey A, et al.
JCI Insight
. 2025 Mar;
10(5).
PMID: 40059827
Chronic kidney diseases (CKDs) are a global health concern, necessitating a comprehensive understanding of their complex pathophysiology. This study explores the use of 2 complementary multidimensional -omics data integration methods...
2.
Bleckwehl T, Babler A, Tebens M, Maryam S, Nyberg M, Bosteen M, et al.
Nat Cardiovasc Res
. 2024 Dec;
4(1):26-44.
PMID: 39715784
Atherosclerosis is a pervasive contributor to ischemic heart disease and stroke. Despite the advance of lipid-lowering therapies and anti-hypertensive agents, the residual risk of an atherosclerotic event remains high, and...
3.
Kim Y, Das V, Kanoo S, Yao H, Stanford S, Bottini N, et al.
Am J Physiol Renal Physiol
. 2024 Nov;
328(1):F68-F81.
PMID: 39589189
SGLT2 inhibitors (SGLT2i) and GLP1 receptor (GLP1R) agonists have kidney protective effects. To better understand their molecular effects, RNA sequencing was performed in SGLT2-positive proximal tubule segments isolated by immunostaining-guided...
4.
Ward H, Anquetil F, Das V, Gibson C, Dovmark T, Kusmartseva I, et al.
Kidney360
. 2024 Nov;
PMID: 39499578
Background: The Network for Pancreatic Organ donors with Diabetes-Kidney (nPOD-K) project was initiated to assess the feasibility of using kidneys from organ donors to enhance understanding of diabetic kidney disease...
5.
Bhayana S, Schytz P, Bisgaard Olesen E, Soh K, Das V
Am J Pathol
. 2024 Aug;
195(1):55-68.
PMID: 39097167
Chronic kidney disease (CKD) and its subset diabetic kidney disease are progressive conditions that affect >850 million people worldwide. Diabetes, hypertension, and glomerulonephritis are the most common causes of CKD,...
6.
Moreno J, Gluud L, Galsgaard E, Hvid H, Mazzoni G, Das V
PLoS One
. 2024 May;
19(5):e0302853.
PMID: 38768139
Background: Chronic Kidney Disease (CKD) and Metabolic dysfunction-associated steatohepatitis (MASH) are metabolic fibroinflammatory diseases. Combining single-cell (scRNAseq) and spatial transcriptomics (ST) could give unprecedented molecular disease understanding at single-cell resolution....
7.
Slabowska A, Pyke C, Hvid H, Jessen L, Baumgart S, Das V
Front Bioinform
. 2024 Apr;
4:1352594.
PMID: 38601476
A major challenge in sequencing-based spatial transcriptomics (ST) is resolution limitations. Tissue sections are divided into hundreds of thousands of spots, where each spot invariably contains a mixture of cell...
8.
Maitra C, Seal D, Das V, De R
Front Mol Biosci
. 2023 Jun;
10:1184748.
PMID: 37293552
Multi-omics studies have enabled us to understand the mechanistic drivers behind complex disease states and progressions, thereby providing novel and actionable biological insights into health status. However, integrating data from...
9.
Buontempo S, Laise P, Hughes J, Trattaro S, Das V, Rencurel C, et al.
Front Neurosci
. 2022 Jun;
16:814144.
PMID: 35645710
The Polycomb Repressive Complex 2 (PRC2) plays important roles in the epigenetic regulation of cellular development and differentiation through H3K27me3-dependent transcriptional repression. Aberrant PRC2 activity has been associated with cancer...
10.
Cox L, Chan J, Rao P, Hamid Z, Glenn J, Jadhav A, et al.
BMC Genomics
. 2021 Dec;
22(1):870.
PMID: 34861817
Background: Dietary high fructose (HFr) is a known metabolic disruptor contributing to development of obesity and diabetes in Western societies. Initial molecular changes from exposure to HFr on liver metabolism...