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Vivek Bhalla

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Articles 71
Citations 1572
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Recent Articles
1.
Sharma Y, Lo R, Tomilin V, Ha K, Deremo H, Pareek A, et al.
JCI Insight . 2024 Oct; 9(22). PMID: 39405114
Mutations in the CLCNKB gene (1p36), encoding the basolateral chloride channel ClC-Kb, cause type 3 Bartter syndrome. We identified a family with a mixed Bartter/Gitelman phenotype and early-onset kidney failure...
2.
da Silva Francisco Jr R, Punj S, Vincent L, Sanapareddy N, Bhalla V, Chertow G, et al.
Kidney Int Rep . 2024 Sep; 9(9):2667-2676. PMID: 39291188
Introduction: Among individuals with high-risk genotypes, the lifetime risk of developing kidney failure is ∼15%, indicating that other genetic variants or nongenetic modifiers likely contribute substantially to an individual patient's...
3.
Maxim D, Wu D, Johnson N, Charu V, Carter J, Anand S, et al.
Res Sq . 2024 Aug; PMID: 39184070
CRISPR-Cas genome editing is transformative; however, there is no simple tool available for determining the optimal genome editing technology to create specific mutations for experimentation or to correct mutations as...
4.
Gaudet A, Zheng X, Kambham N, Bhalla V
Am J Physiol Renal Physiol . 2024 Apr; 326(6):F1016-F1031. PMID: 38601985
Esm-1, endothelial cell-specific molecule-1, is a susceptibility gene for diabetic kidney disease (DKD) and is a secreted proteoglycan, with notable expression in kidney, which attenuates inflammation and albuminuria. However, little...
5.
Tan J, Bhalla V
Clin J Am Soc Nephrol . 2024 Feb; PMID: 38349665
No abstract available.
6.
Hernandez M, Babakhanian M, Chen T, Sarraju A, Seninger C, Ravi V, et al.
J Am Heart Assoc . 2024 Jan; 13(2):e030884. PMID: 38226516
Background: High blood pressure affects approximately 116 million adults in the United States. It is the leading risk factor for death and disability across the world. Unfortunately, over the past...
7.
Shi Y, Bhalla V
bioRxiv . 2023 Nov; PMID: 37961186
Approximately 40% of individuals with chronic kidney disease have type 2 diabetes mellitus, and diabetic kidney disease is the leading cause of end-stage kidney disease worldwide. Inhibitors of sodium-glucose cotransporter...
8.
Hewavitharana P, Schensul S, Lee E, Montez-Rath M, Senarathne S, Liu S, et al.
Kidney Int Rep . 2023 Jul; 8(7):1430-1438. PMID: 37441476
Introduction: Chronic kidney disease of uncertain etiology (CKDu) is a leading cause of death of adults in Sri Lanka's dry region. Methods: We initiated the Kidney Progression Project (KiPP) to...
9.
Gaudet A, Zheng X, Kambham N, Bhalla V
bioRxiv . 2023 Mar; PMID: 36993439
Background: Esm-1, endothelial cell-specific molecule-1, is a susceptibility gene for diabetic kidney disease (DKD) and is a cytokine- and glucose-regulated, secreted proteoglycan, that is notably expressed in kidney and attenuates...
10.
Hernandez M, Bhalla V
Am J Kidney Dis . 2023 Mar; 82(3):333-346. PMID: 36965825
A clinical condition may be missed due to its higher-than-recognized prevalence or inadequate diagnostic screening. Both factors apply to primary aldosteronism, which is woefully underdiagnosed as a cause of hypertension...