Vishnu C Ramani
Overview
Explore the profile of Vishnu C Ramani including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
1582
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0
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Recent Articles
1.
Ackerman S, Pearson C, Gregorio J, Gonzalez J, Kenkel J, Hartmann F, et al.
Nat Cancer
. 2022 Feb;
2(1):18-33.
PMID: 35121890
Innate pattern recognition receptor agonists, including Toll-like receptors (TLRs), alter the tumor microenvironment and prime adaptive antitumor immunity. However, TLR agonists present toxicities associated with widespread immune activation after systemic...
2.
Vences-Catalan F, Rajapaksa R, Kuo C, Miller C, Lee A, Ramani V, et al.
Proc Natl Acad Sci U S A
. 2021 Jun;
118(24).
PMID: 34099563
Tetraspanins are an evolutionary conserved family of proteins involved in multiple aspects of cell physiology, including proliferation, migration and invasion, protein trafficking, and signal transduction; yet their detailed mechanism of...
3.
Razmara A, Sollier E, Kisirkoi G, Baker S, Bellon M, McMillan A, et al.
Clin Exp Metastasis
. 2020 Apr;
37(3):413-424.
PMID: 32335861
Patient-derived orthotopic xenograft (PDOX) models have been verified as a useful method for studying human cancers in mice. Previous studies on the extent of metastases in these models have been...
4.
Tripathi K, Ramani V, Bandari S, Amin R, Brown E, Ritchie J, et al.
Matrix Biol
. 2019 Dec;
88:53-68.
PMID: 31812535
Heparanase is known to enhance the progression of many cancer types and is associated with poor patient prognosis. We recently reported that after patients with multiple myeloma were treated with...
5.
Ramani V, Lemaire C, Triboulet M, Casey K, Heirich K, Renier C, et al.
Breast Cancer Res
. 2019 Aug;
21(1):98.
PMID: 31462307
Background: Circulating tumor cells (CTCs) represent a temporal "snapshot" of a patient's cancer and changes that occur during disease evolution. There is an extensive literature studying CTCs in breast cancer...
6.
Dutta R, Liba O, SoRelle E, Winetraub Y, Ramani V, Jeffrey S, et al.
Nano Lett
. 2019 Mar;
19(4):2334-2342.
PMID: 30895796
Optical coherence tomography (OCT) can be utilized with significant speckle reduction techniques and highly scattering contrast agents for non-invasive, contrast-enhanced imaging of living tissues at the cellular scale. The advantages...
7.
Lemaire C, Liu S, Wilkerson C, Ramani V, Barzanian N, Huang K, et al.
SLAS Technol
. 2018 Jan;
23(1):16-29.
PMID: 29355087
Tumor tissue biopsies are invasive, costly, and collect a limited cell population not completely reflective of patient cancer cell diversity. Circulating tumor cells (CTCs) can be isolated from a simple...
8.
Higgs J, Lee J, Wang H, Ramani V, Chanda D, Hardy C, et al.
Blood Adv
. 2018 Jan;
1(25):2375-2385.
PMID: 29296887
The current treatment options for multiple myeloma (MM) osteolytic lesions are mainly combinations of chemotherapy and other small-molecule inhibitors, but toxic side effects still remain a major concern. Studies have...
9.
Bandari S, Purushothaman A, Ramani V, Brinkley G, Chandrashekar D, Varambally S, et al.
Matrix Biol
. 2017 Sep;
65:104-118.
PMID: 28888912
Summary: We find that anti-myeloma chemotherapy dramatically stimulates secretion of exosomes and alters exosome composition. Exosomes secreted during therapy contain high levels of heparanase on their surface that can degrade...
10.
Kidess-Sigal E, Liu H, Triboulet M, Che J, Ramani V, Visser B, et al.
Oncotarget
. 2016 Nov;
7(51):85349-85364.
PMID: 27863403
Treatment of advanced colorectal cancer (CRC) requires multimodal therapeutic approaches and need for monitoring tumor plasticity. Liquid biopsy biomarkers, including CTCs and ctDNA, hold promise for evaluating treatment response in...