Virginia Hoglund
Overview
Explore the profile of Virginia Hoglund including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
1117
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0
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Recent Articles
1.
Sullivan P, Kumar R, Li W, Hoglund V, Wang L, Zhang Y, et al.
Mol Cancer Ther
. 2022 Jul;
21(10):1608-1621.
PMID: 35877472
Rhabdomyosarcoma (RMS) is the most common soft tissue cancer in children. Treatment outcomes, particularly for relapsed/refractory or metastatic disease, have not improved in decades. The current lack of novel therapies...
2.
Moyes K, Davis A, Hoglund V, Haberthur K, Lieberman N, Kreuser S, et al.
Oncoimmunology
. 2018 Nov;
7(11):e1507668.
PMID: 30377570
Efforts to reduce immunosuppression in the solid tumor microenvironment by blocking the recruitment or polarization of tumor associated macrophages (TAM), or myeloid derived suppressor cells (MDSCs), have gained momentum in...
3.
Lieberman N, DeGolier K, Kovar H, Davis A, Hoglund V, Stevens J, et al.
Neuro Oncol
. 2018 Sep;
21(1):83-94.
PMID: 30169876
Background: Diffuse intrinsic pontine glioma (DIPG) is a uniformly fatal CNS tumor diagnosed in 300 American children per year. Radiation is the only effective treatment and extends overall survival to...
4.
Taraseviciute A, Tkachev V, Ponce R, Turtle C, Snyder J, Liggitt H, et al.
Cancer Discov
. 2018 Mar;
8(6):750-763.
PMID: 29563103
Chimeric antigen receptor (CAR) T-cell immunotherapy has revolutionized the treatment of refractory leukemias and lymphomas, but is associated with significant toxicities, namely cytokine release syndrome (CRS) and neurotoxicity. A major...
5.
Gardner R, Finney O, Annesley C, Brakke H, Summers C, Leger K, et al.
Blood
. 2017 Apr;
129(25):3322-3331.
PMID: 28408462
Transitioning CD19-directed chimeric antigen receptor (CAR) T cells from early-phase trials in relapsed patients to a viable therapeutic approach with predictable efficacy and low toxicity for broad application among patients...
6.
Haberthur K, Brennan K, Hoglund V, Balcaitis S, Chinn H, Davis A, et al.
Cancer Biol Ther
. 2016 Nov;
17(12):1253-1265.
PMID: 27834580
Adult brain tumors establish an immunosuppressive tumor microenvironment as a modality of immune escape, with several immunotherapies designed to overcome this barrier. However, the relationship between tumor cells and immune...
7.
Moyes K, Lieberman N, Kreuser S, Chinn H, Winter C, Deutsch G, et al.
Hum Gene Ther
. 2016 Oct;
28(2):200-215.
PMID: 27758144
In spite of their successes against hematologic malignancies, immunotherapeutic interventions for the treatment of patients with glioblastoma (GBM) have thus far been unsuccessful. This is in part due to the...
8.
Kunkele A, Johnson A, Rolczynski L, Chang C, Hoglund V, Kelly-Spratt K, et al.
Cancer Immunol Res
. 2015 Jan;
3(4):368-79.
PMID: 25576337
Chimeric antigen receptor (CAR) development is biased toward selecting constructs that elicit the highest magnitude of T-cell functional outputs. Here, we show that components of CAR extracellular spacer and cytoplasmic...
9.
Majesky M, Dong X, Hoglund V, Daum G, Mahoney Jr W
Cells Tissues Organs
. 2011 Oct;
195(1-2):73-81.
PMID: 22005572
Recent observations suggest that the adventitial layer of blood vessels exhibits properties resembling a stem/progenitor cell niche. Progenitor cells have been isolated from the adventitia of both murine and human...
10.
Majesky M, Dong X, Hoglund V, Mahoney Jr W, Daum G
Arterioscler Thromb Vasc Biol
. 2011 Jun;
31(7):1530-9.
PMID: 21677296
Conventional views of the tunica adventitia as a poorly organized layer of vessel wall composed of fibroblasts, connective tissue, and perivascular nerves are undergoing revision. Recent studies suggest that the...