William M Mahoney Jr
Overview
Explore the profile of William M Mahoney Jr including associated specialties, affiliations and a list of published articles.
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17
Citations
597
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0
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Recent Articles
1.
Brewer C, Nelson B, Wakenight P, Collins S, Okamura D, Dong X, et al.
Dev Cell
. 2021 Oct;
56(19):2722-2740.e6.
PMID: 34610329
Spiny mice (Acomys cahirinus) are terrestrial mammals that evolved unique scar-free regenerative wound-healing properties. Myofibroblasts (MFs) are the major scar-forming cell type in skin. We found that following traumatic injury...
2.
Bahrami A, Gunaje J, Hayes B, Riehle K, Kenerson H, Yeung R, et al.
PLoS One
. 2014 Oct;
9(10):e108505.
PMID: 25290689
Liver fibrosis is mediated by hepatic stellate cells (HSCs), which respond to a variety of cytokine and growth factors to moderate the response to injury and create extracellular matrix at...
3.
Hayes B, Riehle K, Shimizu-Albergine M, Bauer R, Hudkins K, Johansson F, et al.
PLoS One
. 2014 Mar;
9(3):e92925.
PMID: 24667490
Chronic liver injury leads to fibrosis, cirrhosis, and loss of liver function. Liver cirrhosis is the 12th leading cause of death in the United States, and it is the primary...
4.
Ieronimakis N, Hays A, Janebodin K, Mahoney Jr W, Duffield J, Majesky M, et al.
J Mol Cell Cardiol
. 2013 Aug;
63:122-34.
PMID: 23911435
In Duchenne muscular dystrophy (DMD), progressive accumulation of cardiac fibrosis promotes heart failure. While the cellular origins of fibrosis in DMD hearts remain enigmatic, fibrotic tissue conspicuously forms near the...
5.
Weyers J, Schwartz S, Minami E, Carlson D, Dupras S, Weitz K, et al.
J Am Heart Assoc
. 2013 Jun;
2(3):e000202.
PMID: 23723253
Background: With recent advances in therapeutic applications of stem cells, cell engraftment has become a promising therapy for replacing injured myocardium after infarction. The survival and function of injected cells,...
6.
Mahoney Jr W, Gunaje J, Daum G, Dong X, Majesky M
PLoS One
. 2013 May;
8(4):e61421.
PMID: 23637832
Hedgehog (Hh) signaling plays fundamental roles in morphogenesis, tissue repair, and human disease. Initiation of Hh signaling is controlled by the interaction of two multipass membrane proteins, patched (Ptc) and...
7.
Weyers J, Carlson D, Murry C, Schwartz S, Mahoney Jr W
J Vis Exp
. 2012 Feb;
(60):e3740.
PMID: 22353785
Visualization of the vasculature is becoming increasingly important for understanding many different disease states. While several techniques exist for imaging vasculature, few are able to visualize the vascular network as...
8.
Majesky M, Dong X, Hoglund V, Daum G, Mahoney Jr W
Cells Tissues Organs
. 2011 Oct;
195(1-2):73-81.
PMID: 22005572
Recent observations suggest that the adventitial layer of blood vessels exhibits properties resembling a stem/progenitor cell niche. Progenitor cells have been isolated from the adventitia of both murine and human...
9.
Majesky M, Dong X, Hoglund V, Mahoney Jr W, Daum G
Arterioscler Thromb Vasc Biol
. 2011 Jun;
31(7):1530-9.
PMID: 21677296
Conventional views of the tunica adventitia as a poorly organized layer of vessel wall composed of fibroblasts, connective tissue, and perivascular nerves are undergoing revision. Recent studies suggest that the...
10.
Gunaje J, Bahrami A, Schwartz S, Daum G, Mahoney Jr W
Am J Physiol Cell Physiol
. 2011 May;
301(2):C478-89.
PMID: 21593453
Regulator of G protein signaling (RGS) proteins, and notably members of the RGS-R4 subfamily, control vasocontractility by accelerating the inactivation of Gα-dependent signaling. RGS5 is the most highly and differently...