Virendra K Bhasin
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Explore the profile of Virendra K Bhasin including associated specialties, affiliations and a list of published articles.
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14
Citations
113
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Recent Articles
1.
Singh S, Khandare R, Sharma M, Bhasin V, Bhat S
Nat Prod Commun
. 2014 Apr;
9(3):299-302.
PMID: 24689199
Conjugated acid derivatives containing nitrogen have been synthesized from the simple acyclic monoterpene citral, using various reactions, including Wittig, Baylis Hillman, amide and ester condensations. Similarly, amine peroxides were synthesized...
2.
Mallick P, Singh R, Singh O, Singh A, Bhasin V, Valecha N
Infect Genet Evol
. 2013 Oct;
20:407-12.
PMID: 24126360
The positive selection of a nucleotide substitution in exon 2 of Plasmodium falciparum chloroquine resistance transporter (pfcrt) gene (mutation responsible for chloroquine resistance) causes a reduction in variation of neutral...
3.
Mallick P, Sutton P, Singh R, Singh O, Dash A, Singh A, et al.
Infect Genet Evol
. 2013 Jul;
19:164-75.
PMID: 23871774
Efforts to control malignant malaria caused by Plasmodium falciparum are hampered by the parasite's acquisition of resistance to antimalarial drugs, e.g., chloroquine. This necessitates evaluating the spread of chloroquine resistance...
4.
Yadav N, Dixit S, Bhattacharya A, Mishra L, Sharma M, Awasthi S, et al.
Chem Biol Drug Des
. 2012 Mar;
80(2):340-7.
PMID: 22429524
Twenty-seven novel chalcone derivatives were synthesized using Claisen-Schmidt condensation and their antimalarial activity against asexual blood stages of Plasmodium falciparum was determined. Antiplasmodial IC(50) (half-maximal inhibitory concentration) activity of a...
5.
Mallick P, Joshi H, Valecha N, Sharma S, Eapen A, Bhatt R, et al.
Malar J
. 2012 Jan;
11:16.
PMID: 22236376
Background: Chloroquine resistance (CQR) phenotype in Plasmodium falciparum is associated with mutations in pfcrt and pfmdr-1 genes. Mutations at amino acid position 72-76 of pfcrt gene, here defined as pfcrt...
6.
Mishra L, Bhattacharya A, Sharma M, Bhasin V
Am J Trop Med Hyg
. 2010 Jan;
82(1):148-50.
PMID: 20065012
Most malaria endemic regions are co-infested with HIV infection. Treatment of one may affect outcome of the other in co-infected individuals. HIV protease inhibitors, indinavir or nelfinavir, are important antiretroviral...
7.
Bhattacharya A, Mishra L, Sharma M, Awasthi S, Bhasin V
Eur J Med Chem
. 2009 Mar;
44(9):3388-93.
PMID: 19269069
Use of artemisinin based combination therapies (ACTs) is increasing in treatment of malaria. Their extensive and indiscriminate deployment will ultimately lead to selection of resistance. Thus, alternate ACTs are needed....
8.
Mishra L, Bhattacharya A, Bhasin V
Acta Trop
. 2008 Dec;
109(3):194-8.
PMID: 19063856
Resistance to synthetic first-line antimalarial drugs is considered to be a major cause of increased malaria morbidity and mortality. Use of artemisinin-based combination therapies (ACTs) is being encouraged to reduce...
9.
Bhattacharya A, Mishra L, Bhasin V
Am J Trop Med Hyg
. 2008 May;
78(5):721-8.
PMID: 18458303
Currently available artemisinin-based combination therapies (ACTs) for malaria are inadequate. There remains an enormous unmet need for alternate artemisinin-based combination therapies. One of the fastest methods to identify promising artemisinin-based...
10.