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Vineeth Chandran Suja

Explore the profile of Vineeth Chandran Suja including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 82
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Recent Articles
1.
Knudsen A, Arney D, Butterfield R, Sims N, Suja V, Peterfreund R
J Clin Monit Comput . 2024 Sep; 39(1):217-232. PMID: 39299986
Critically ill or anesthetized patients commonly receive pump-driven intravenous infusions of potent, fast-acting, short half-life medications for managing hemodynamics. Stepwise dosing, e.g. over 3-5 min, adjusts physiologic responses. Flow rates...
2.
Kapate N, Dunne M, Gottlieb A, Mukherji M, Suja V, Prakash S, et al.
Adv Healthc Mater . 2024 Apr; 14(5):e2304144. PMID: 38581301
Adoptive cell therapies are dramatically altering the treatment landscape of cancer. However, treatment of solid tumors remains a major unmet need, in part due to limited adoptive cell infiltration into...
3.
Kumbhojkar N, Prakash S, Fukuta T, Adu-Berchie K, Kapate N, An R, et al.
Nat Biomed Eng . 2024 Feb; 8(5):579-592. PMID: 38424352
Tumour-associated neutrophils can exert antitumour effects but can also assume a pro-tumoural phenotype in the immunosuppressive tumour microenvironment. Here we show that neutrophils can be polarized towards the antitumour phenotype...
4.
Kapate N, Liao R, Sodemann R, Stinson T, Prakash S, Kumbhojkar N, et al.
PNAS Nexus . 2024 Jan; 3(1):pgad434. PMID: 38187808
Traumatic brain injury (TBI) is a debilitating disease with no current therapies outside of acute clinical management. While acute, controlled inflammation is important for debris clearance and regeneration after injury,...
5.
Wang L, Gao Y, Suja V, Boucher M, Shaha S, Kapate N, et al.
Sci Transl Med . 2024 Jan; 16(728):eadk5413. PMID: 38170792
The choroid plexus (ChP) of the brain plays a central role in orchestrating the recruitment of peripheral leukocytes into the central nervous system (CNS) through the blood-cerebrospinal fluid (BCSF) barrier...
6.
Suja V, Qi Q, Halloran K, Zhang J, Shaha S, Prakash S, et al.
PNAS Nexus . 2023 Oct; 2(10):pgad317. PMID: 37901442
Subcutaneous (subQ) injection is a common route for delivering biotherapeutics, wherein pharmacokinetics is largely influenced by drug transport in a complex subQ tissue microenvironment. The selection of good drug candidates...
7.
Huang Y, Suja V, Yang M, Malkovskiy A, Tandon A, Colom A, et al.
J Colloid Interface Sci . 2023 Oct; 653(Pt B):1196-1204. PMID: 37793246
Hypothesis: Response of lipid bilayers to external mechanical stimuli is an active area of research with implications for fundamental and synthetic cell biology. Developing novel tools for systematically imposing mechanical...
8.
Prakash S, Kumbhojkar N, Lu A, Kapate N, Suja V, Park K, et al.
ACS Nano . 2023 Aug; 17(16):15918-15930. PMID: 37565806
Natural killer (NK) cell therapies have emerged as a potential therapeutic approach to various cancers. Their efficacy, however, is limited by their low persistence and anergy. Current approaches to sustain...
9.
Kapate N, Dunne M, Kumbhojkar N, Prakash S, Wang L, Graveline A, et al.
Proc Natl Acad Sci U S A . 2023 Apr; 120(17):e2221535120. PMID: 37075071
Multiple sclerosis (MS) is an incurable autoimmune disease and is currently treated by systemic immunosuppressants with off-target side effects. Although aberrant myeloid function is often observed in MS plaques in...
10.
Adebowale K, Liao R, Suja V, Kapate N, Lu A, Gao Y, et al.
Adv Mater . 2023 Feb; 36(43):e2210059. PMID: 36809574
Cell therapies are emerging as a promising new therapeutic modality in medicine, generating effective treatments for previously incurable diseases. Clinical success of cell therapies has energized the field of cellular...