Gerald G Fuller
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Explore the profile of Gerald G Fuller including associated specialties, affiliations and a list of published articles.
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105
Citations
1097
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Recent Articles
1.
Prossnitz A, Nguyen L, Eckman N, Borkar S, Tetef S, Autzen A, et al.
Adv Sci (Weinh)
. 2025 Jan;
12(8):e2409604.
PMID: 39764759
Biopharmaceuticals are the fastest-growing class of drugs in the healthcare industry, but their global reach is severely limited by their propensity for rapid aggregation. Currently, surfactant excipients such as polysorbates...
2.
Braunreuther M, Arenhoevel J, Bej R, Moose C, Mall M, Haag R, et al.
Soft Matter
. 2024 Dec;
21(3):427-434.
PMID: 39704007
Mucus is composed of a complex network of mucin polymers connected by disulfide bonds. In muco-obstructive diseases, an increase in mucin disulfide crosslinks contributes to pathologic mucus formation, characterized by...
3.
Borkar S, Baumli P, Vance T, Sharma E, Shi X, Wu J, et al.
Proc Natl Acad Sci U S A
. 2024 Jul;
121(31):e2407501121.
PMID: 39042697
This study explores the impact of electrostatic interactions and hydrogen bonding on tear film stability, a crucial factor for ocular surface health. While mucosal and meibomian layers have been extensively...
4.
Liegeois M, Braunreuther M, Charbit A, Raymond W, Tang M, Woodruff P, et al.
JCI Insight
. 2024 Jun;
9(15).
PMID: 38889046
Mucus plugs occlude airways to obstruct airflow in asthma. Studies in patients and in mouse models show that mucus plugs occur in the context of type 2 inflammation, and studies...
5.
Cai P, Braunreuther M, Shih A, Spakowitz A, Fuller G, Heilshorn S
APL Bioeng
. 2024 May;
8(2):026112.
PMID: 38721267
Intestinal health heavily depends on establishing a mucus layer within the gut with physical properties that strike a balance between being sufficiently elastic to keep out harmful pathogens yet viscous...
6.
Michalaki E, Surya V, Rodriguez-Hakim M, Fuller G, Dunn A
FASEB J
. 2023 Oct;
37(12):e23240.
PMID: 37902497
One-way valves within lymphatic vessels are required for the efficient drainage of lymphatic fluids. Fluid flow is proposed to be a key cue in regulating both the formation and maintenance...
7.
Huang Y, Suja V, Yang M, Malkovskiy A, Tandon A, Colom A, et al.
J Colloid Interface Sci
. 2023 Oct;
653(Pt B):1196-1204.
PMID: 37793246
Hypothesis: Response of lipid bilayers to external mechanical stimuli is an active area of research with implications for fundamental and synthetic cell biology. Developing novel tools for systematically imposing mechanical...
8.
Baumli P, Liu C, Bekcic A, Fuller G
Adv Biol (Weinh)
. 2023 Jun;
7(8):e2300043.
PMID: 37271859
The collective adhesive behavior of epithelial cell layers mediated by complex macromolecular fluid environments plays a vital role in many biological processes. Mucins, a family of highly glycosylated proteins, are...
9.
Zawala J, Miguet J, Rastogi P, Atasi O, Borkowski M, Scheid B, et al.
Adv Colloid Interface Sci
. 2023 Jun;
317:102916.
PMID: 37269558
The formation of motion-induced dynamic adsorption layers of surfactants at the surface of rising bubbles is a widely accepted phenomenon. Although their existence and formation kinetics have been theoretically postulated...
10.
Klich J, Kasse C, Mann J, Huang Y, dAquino A, Grosskopf A, et al.
Adv Ther (Weinh)
. 2023 Jan;
6(1).
PMID: 36684707
Monoclonal antibodies are a staple in modern pharmacotherapy. Unfortunately, these biopharmaceuticals are limited by their tendency to aggregate in formulation, resulting in poor stability and often requiring low concentration drug...