Vincent Nieto
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Explore the profile of Vincent Nieto including associated specialties, affiliations and a list of published articles.
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18
Citations
803
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Recent Articles
1.
Kumar N, Grosser M, Wan S, Schator D, Ahn E, Jedel E, et al.
Invest Ophthalmol Vis Sci
. 2025 Feb;
66(2):31.
PMID: 39932472
Purpose: Healthy corneas resist colonization by virtually all microbes, yet contact lens wear can predispose the cornea to sight-threatening infection with Pseudomonas aeruginosa. Here, we explored how lens wear changes...
2.
Kumar N, Grosser M, Wan S, Schator D, Ahn E, Jedel E, et al.
bioRxiv
. 2024 Dec;
PMID: 39677621
Purpose: Healthy corneas resist colonization by virtually all microbes yet contact lens wear can predispose the cornea to sight-threatening infection with . Here, we explored how lens wear changes corneal...
3.
Kroken A, Klein K, Mitchell P, Nieto V, Jedel E, Evans D, et al.
mSphere
. 2023 Aug;
8(5):e0035123.
PMID: 37589460
Pathogenesis of infections can include bacterial survival inside epithelial cells. Previously, we showed that this involves multiple roles played by the type three secretion system (T3SS), and specifically the effector...
4.
Kroken A, Klein K, Mitchell P, Nieto V, Jedel E, Evans D, et al.
bioRxiv
. 2023 Feb;
PMID: 36824932
Pathogenesis of Pseudomonas aeruginosa infections can include bacterial survival inside epithelial cells. Previously, we showed this involves multiple roles played by the type three-secretion system (T3SS), and specifically the effector...
5.
Hilpert C, Beranger L, Souza P, Vainikka P, Nieto V, Marrink S, et al.
J Chem Inf Model
. 2023 Jan;
63(3):702-710.
PMID: 36656159
The MArtini Database (MAD - https://mad.ibcp.fr) is a web server designed for the sharing of structures and topologies of molecules parametrized with the Martini coarse-grained (CG) force field. MAD can...
6.
Kumar N, Nieto V, Kroken A, Jedel E, Grosser M, Hallsten M, et al.
mBio
. 2022 Nov;
13(6):e0274222.
PMID: 36374039
Within epithelial cells, Pseudomonas aeruginosa depends on its type III secretion system (T3SS) to escape vacuoles and replicate rapidly in the cytosol. Previously, it was assumed that intracellular subpopulations remaining...
7.
Kroken A, Kumar N, Yahr T, Smith B, Nieto V, Horneman H, et al.
PLoS Pathog
. 2022 Feb;
18(2):e1010306.
PMID: 35130333
The Pseudomonas aeruginosa toxin ExoS, secreted by the type III secretion system (T3SS), supports intracellular persistence via its ADP-ribosyltransferase (ADPr) activity. For epithelial cells, this involves inhibiting vacuole acidification, promoting...
8.
Wan S, Datta A, Flandrin O, Metruccio M, Ma S, Nieto V, et al.
FASEB J
. 2021 Sep;
35(10):e21899.
PMID: 34569661
The cornea of the eye differs from other mucosal surfaces in that it lacks a viable bacterial microbiome and by its unusually high density of sensory nerve endings. Here, we...
9.
Tabor L, Grosser M, Metruccio M, Kumar N, Wu Y, Nieto V, et al.
Ocul Surf
. 2021 Jul;
22:94-102.
PMID: 34332149
Purpose: Previously, we showed that tear fluid protects corneal epithelial cells against Pseudomonas aeruginosa without suppressing bacterial viability. Here, we studied how tear fluid affects bacterial gene expression. Methods: RNA-sequencing...
10.
Souza P, Alessandri R, Barnoud J, Thallmair S, Faustino I, Grunewald F, et al.
Nat Methods
. 2021 Mar;
18(4):382-388.
PMID: 33782607
The coarse-grained Martini force field is widely used in biomolecular simulations. Here we present the refined model, Martini 3 ( http://cgmartini.nl ), with an improved interaction balance, new bead types...