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Vincent Meynier

Explore the profile of Vincent Meynier including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 201
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Recent Articles
1.
Sikarwar J, Meynier V, Tisne C
J Mol Biol . 2025 Feb; :168989. PMID: 39938738
Mitochondrial pre-tRNA maturation is a multi-step process involving the removal of the 5'-leader by PRORP, 3'-trailer processing by ELAC2, 3'-CCA addition by TRNT1, and the incorporation of post-transcriptional modifications. In...
2.
Arias A, Neehus A, Ogishi M, Meynier V, Krebs A, Lazarov T, et al.
Nature . 2024 Aug; 633(8029):417-425. PMID: 39198650
Severe defects in human IFNγ immunity predispose individuals to both Bacillus Calmette-Guérin disease and tuberculosis, whereas milder defects predispose only to tuberculosis. Here we report two adults with recurrent pulmonary...
3.
Meynier V, Hardwick S, Catala M, Roske J, Oerum S, Chirgadze D, et al.
Nat Commun . 2024 Jun; 15(1):4683. PMID: 38824131
The human mitochondrial genome is transcribed into two RNAs, containing mRNAs, rRNAs and tRNAs, all dedicated to produce essential proteins of the respiratory chain. The precise excision of tRNAs by...
4.
Smoczynski J, Yared M, Meynier V, Barraud P, Tisne C
Acc Chem Res . 2024 Feb; PMID: 38331425
ConspectusRNA modification is a co- or post-transcriptional process by which specific nucleotides are chemically altered by enzymes after their initial incorporation into the RNA chain, expanding the chemical and functional...
5.
Meynier V, Iannazzo L, Catala M, Oerum S, Braud E, Atdjian C, et al.
Nucleic Acids Res . 2022 May; 50(10):5793-5806. PMID: 35580049
Chemical synthesis of RNA conjugates has opened new strategies to study enzymatic mechanisms in RNA biology. To gain insights into poorly understood RNA nucleotide methylation processes, we developed a new...
6.
Oerum S, Meynier V, Catala M, Tisne C
Nucleic Acids Res . 2021 May; 49(13):7239-7255. PMID: 34023900
Gene expression is regulated at many levels including co- or post-transcriptionally, where chemical modifications are added to RNA on riboses and bases. Expression control via RNA modifications has been termed...