Vincent Gardeux
Overview
Explore the profile of Vincent Gardeux including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
1088
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Recent Articles
1.
Erdil E, Becker A, Schwyzer M, Martinez-Tellez B, Ruiz J, Sartoretti T, et al.
Nat Commun
. 2024 Nov;
15(1):10022.
PMID: 39562561
No abstract available.
2.
Gardeux V, Bevers R, David F, Rosschaert E, Rochepeau R, Deplancke B
Elife
. 2024 Oct;
12.
PMID: 39431984
Genome-wide association studies have advanced our understanding of complex traits, but studying how a GWAS variant can affect a specific trait in the human population remains challenging due to environmental...
3.
Kribelbauer-Swietek J, Pushkarev O, Gardeux V, Faltejskova K, Russeil J, van Mierlo G, et al.
Nat Genet
. 2024 Oct;
56(10):2199-2212.
PMID: 39363017
Many enhancers control gene expression by assembling regulatory factor clusters, also referred to as condensates. This process is vital for facilitating enhancer communication and establishing cellular identity. However, how DNA...
4.
Erdil E, Becker A, Schwyzer M, Martinez-Tellez B, Ruiz J, Sartoretti T, et al.
Nat Commun
. 2024 Sep;
15(1):8402.
PMID: 39333526
The standard method for identifying active Brown Adipose Tissue (BAT) is [F]-Fluorodeoxyglucose ([F]-FDG) PET/CT imaging, which is costly and exposes patients to radiation, making it impractical for population studies. These...
5.
Pushkarev O, van Mierlo G, Kribelbauer J, Saelens W, Gardeux V, Deplancke B
Genome Biol
. 2024 Jul;
25(1):190.
PMID: 39026229
Background: Interactions among cis-regulatory elements (CREs) play a crucial role in gene regulation. Various approaches have been developed to map these interactions genome-wide, including those relying on interindividual epigenomic variation...
6.
Ferrero R, Rainer P, Rumpler M, Russeil J, Zachara M, Pezoldt J, et al.
Cell Metab
. 2024 May;
36(7):1566-1585.e9.
PMID: 38729152
Adipose tissue plasticity is orchestrated by molecularly and functionally diverse cells within the stromal vascular fraction (SVF). Although several mouse and human adipose SVF cellular subpopulations have by now been...
7.
Pezoldt J, Wiechers C, Zou M, Litovchenko M, Biocanin M, Beckstette M, et al.
Nat Commun
. 2022 Nov;
13(1):7227.
PMID: 36433946
Gut-draining mesenteric lymph nodes (LN) provide the framework to shape intestinal adaptive immune responses. Based on the transcriptional signatures established by our previous work, the composition and immunomodulatory function of...
8.
Chen W, Guillaume-Gentil O, Rainer P, Gabelein C, Saelens W, Gardeux V, et al.
Nature
. 2022 Aug;
608(7924):733-740.
PMID: 35978187
Single-cell transcriptomics (scRNA-seq) has greatly advanced our ability to characterize cellular heterogeneity. However, scRNA-seq requires lysing cells, which impedes further molecular or functional analyses on the same cells. Here, we...
9.
Llimos G, Gardeux V, Koch U, Kribelbauer J, Hafner A, Alpern D, et al.
Nat Commun
. 2022 Apr;
13(1):2042.
PMID: 35440565
Non-coding variants coordinate transcription factor (TF) binding and chromatin mark enrichment changes over regions spanning >100 kb. These molecularly coordinated regions are named "variable chromatin modules" (VCMs), providing a conceptual...
10.
Li H, Janssens J, De Waegeneer M, Kolluru S, Davie K, Gardeux V, et al.
Science
. 2022 Mar;
375(6584):eabk2432.
PMID: 35239393
For more than 100 years, the fruit fly has been one of the most studied model organisms. Here, we present a single-cell atlas of the adult fly, Tabula , that...