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Vincent Cabeli

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Recent Articles
1.
Schmauch B, Cabeli V, Domingues O, Le Douget J, Hardy A, Belbahri R, et al.
iScience . 2025 Jan; 28(1):111638. PMID: 39868035
Over the last decade, Hippo signaling has emerged as a major tumor-suppressing pathway. Its dysregulation is associated with abnormal expression of and -family genes. Recent works have highlighted the role...
2.
Simon F, Comes M, Tocci T, Dupuis L, Cabeli V, Lagrange N, et al.
Elife . 2025 Jan; 13. PMID: 39819525
Live-cell microscopy routinely provides massive amounts of time-lapse images of complex cellular systems under various physiological or therapeutic conditions. However, this wealth of data remains difficult to interpret in terms...
3.
Gross B, Dauvin A, Cabeli V, Kmetzsch V, El Khoury J, Dissez G, et al.
Sci Rep . 2024 Jul; 14(1):17064. PMID: 39048590
Deep learning (DL) has shown potential to provide powerful representations of bulk RNA-seq data in cancer research. However, there is no consensus regarding the impact of design choices of DL...
4.
Ribeiro-Dantas M, Li H, Cabeli V, Dupuis L, Simon F, Hettal L, et al.
iScience . 2024 May; 27(5):109736. PMID: 38711452
Discovering causal effects is at the core of scientific investigation but remains challenging when only observational data are available. In practice, causal networks are difficult to learn and interpret, and...
5.
Muzellec B, Telenczuk M, Cabeli V, Andreux M
Bioinformatics . 2023 Sep; 39(9). PMID: 37669147
Summary: We present PyDESeq2, a python implementation of the DESeq2 workflow for differential expression analysis on bulk RNA-seq data. This re-implementation yields similar, but not identical, results: it achieves higher...
6.
Sella N, Hamy A, Cabeli V, Darrigues L, Lae M, Reyal F, et al.
NPJ Digit Med . 2022 Aug; 5(1):113. PMID: 35948579
Despite unprecedented amount of information now available in medical records, health data remain underexploited due to their heterogeneity and complexity. Simple charts and hypothesis-driven statistics can no longer apprehend the...
7.
Desterke C, Petit L, Sella N, Chevallier N, Cabeli V, Coquelin L, et al.
iScience . 2020 Jun; 23(6):101222. PMID: 32535025
The cardinal property of bone marrow (BM) stromal cells is their capacity to contribute to hematopoietic stem cell (HSC) niches by providing mediators assisting HSC functions. In this study we...
8.
Cabeli V, Verny L, Sella N, Uguzzoni G, Verny M, Isambert H
PLoS Comput Biol . 2020 May; 16(5):e1007866. PMID: 32421707
The precise diagnostics of complex diseases require to integrate a large amount of information from heterogeneous clinical and biomedical data, whose direct and indirect interdependences are notoriously difficult to assess....