Vinay S Mahajan
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Explore the profile of Vinay S Mahajan including associated specialties, affiliations and a list of published articles.
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43
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2335
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Recent Articles
11.
Kaneko N, Kuo H, Boucau J, Farmer J, Allard-Chamard H, Mahajan V, et al.
SSRN
. 2020 Aug;
:3652322.
PMID: 32742244
Humoral responses in COVID-19 disease are often of limited durability, as seen with other human coronavirus epidemics. To address the underlying etiology, we examined postmortem thoracic lymph nodes and spleens...
12.
Perugino C, Kaneko N, Maehara T, Mattoo H, Kers J, Allard-Chamard H, et al.
J Allergy Clin Immunol
. 2020 Jun;
147(1):368-382.
PMID: 32485263
Background: IgG-related disease (IgG-RD) is an immune-mediated fibrotic disorder that has been linked to CD4 cytotoxic T lymphocytes (CD4CTLs). The effector phenotype of CD4CTLs and the relevance of both CD8...
13.
Maehara T, Kaneko N, Perugino C, Mattoo H, Kers J, Allard-Chamard H, et al.
J Clin Invest
. 2020 Jan;
130(5):2451-2464.
PMID: 31990684
Systemic sclerosis (SSc) is an autoimmune fibrotic disease whose pathogenesis is poorly understood and lacks effective therapies. We undertook quantitative analyses of T cell infiltrates in the skin of 35...
14.
Mahajan V, Demissie E, Alsufyani F, Kumari S, Yuen G, Viswanadham V, et al.
J Immunol
. 2019 Nov;
204(1):49-57.
PMID: 31740487
The control of cytoskeletal dynamics by dedicator of cytokinesis 2 (DOCK2), a hematopoietic cell-specific actin effector protein, has been implicated in TCR signaling and T cell migration. Biallelic mutations in...
15.
16.
Allard-Chamard H, Mahajan V
Clin Lab Med
. 2019 Nov;
39(4):699-708.
PMID: 31668279
For decades, autoantibody detection has comprised the bulk of clinical laboratory immunology. However, most immune disorders are caused by imbalances in both humoral and cellular immunity. Our knowledge of the...
17.
Farmer J, Mahajan V
Clin Lab Med
. 2019 Nov;
39(4):685-697.
PMID: 31668278
Primary immunodeficiency diseases are a heterogeneous group of rare inherited disorders of innate or adaptive immune system function. Patients with primary immunodeficiencies typically present with recurrent and severe infections in...
18.
Farmer J, Allard-Chamard H, Sun N, Ahmad M, Bertocchi A, Mahajan V, et al.
Sci Signal
. 2019 Oct;
12(604).
PMID: 31641080
Transitional B cells must actively undergo selection for self-tolerance before maturing into their resting follicular B cell successors. We found that metabolic quiescence was acquired at the follicular B cell...
19.
Newman J, Shaver A, Sheehan J, Mallal S, Stone J, Pillai S, et al.
Mol Genet Genomic Med
. 2019 Apr;
7(6):e686.
PMID: 30993913
Background: Family screening of a 48-year-old male with recently diagnosed IgG4-related disease (IgG4-RD) revealed unanticipated elevations in plasma IgG4 in his two healthy teenaged sons. Methods: We performed gene sequencing,...
20.
Mahajan V, Alsufyani F, Mattoo H, Rosenberg I, Pillai S
Glycobiology
. 2019 Jan;
29(3):222-228.
PMID: 30597004
We used Casd1-deficient mice to confirm that this enzyme is responsible for 9-O-acetylation of sialic acids in vivo. We observed a complete loss of 9-O-acetylation of sialic acid on the...