Vinay Ayyappan
Overview
Explore the profile of Vinay Ayyappan including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
223
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Recent Articles
11.
Viswanath P, Batsios G, Ayyappan V, Taglang C, Gillespie A, Larson P, et al.
Neuro Oncol
. 2021 Apr;
23(9):1509-1522.
PMID: 33864084
Background: Telomerase reverse transcriptase (TERT) is essential for tumor proliferation, including in low-grade oligodendrogliomas (LGOGs). Since TERT is silenced in normal cells, it is also a therapeutic target. Therefore, noninvasive...
12.
Ayyappan V, Wat R, Barber C, Vivelo C, Gauch K, Visanpattanasin P, et al.
Nucleic Acids Res
. 2020 Nov;
49(D1):D261-D265.
PMID: 33137182
ADP-ribosylation is a protein modification responsible for biological processes such as DNA repair, RNA regulation, cell cycle and biomolecular condensate formation. Dysregulation of ADP-ribosylation is implicated in cancer, neurodegeneration and...
13.
Ayyappan V, Chang A, Zhang C, Paidi S, Bordett R, Liang T, et al.
ACS Sens
. 2020 Oct;
5(10):3281-3289.
PMID: 33092347
Identification and classification of leukemia cells in a rapid and label-free fashion is clinically challenging and thus presents a prime arena for implementing new diagnostic tools. Quantitative phase imaging, which...
14.
Ayyappan V, Wat R, Barber C, Vivelo C, Gauch K, Visanpattanasin P, et al.
bioRxiv
. 2020 Sep;
PMID: 32995784
ADP-ribosylation is a protein modification responsible for biological processes such as DNA repair, RNA regulation, cell cycle, and biomolecular condensate formation. Dysregulation of ADP-ribosylation is implicated in cancer, neurodegeneration, and...
15.
Sonkar K, Ayyappan V, Tressler C, Adelaja O, Cai R, Cheng M, et al.
NMR Biomed
. 2019 Jun;
32(10):e4112.
PMID: 31184789
Activated choline metabolism is a hallmark of carcinogenesis and tumor progression, which leads to elevated levels of phosphocholine and glycerophosphocholine in all types of cancer tested so far. Magnetic resonance...
16.
Vivelo C, Ayyappan V, Leung A
Biochem Pharmacol
. 2019 May;
167:3-12.
PMID: 31077644
ADP-ribosylation-the addition of one or multiple ADP-ribose units onto proteins-is a therapeutically important post-translational modification implicated in cancer, neurodegeneration, and infectious diseases. The protein modification regulates a broad range of...
17.
Kalesh K, Lukauskas S, Borg A, Snijders A, Ayyappan V, Leung A, et al.
Sci Rep
. 2019 May;
9(1):6655.
PMID: 31040352
ADP-ribosylation is integral to a diverse range of cellular processes such as DNA repair, chromatin regulation and RNA processing. However, proteome-wide investigation of its cellular functions has been limited due...