Vinay Ayyappan
Overview
Explore the profile of Vinay Ayyappan including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
223
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Recent Articles
1.
Tressler C, Sonkar K, Cheng M, Ayyappan V, Cai R, Glunde K
Transl Oncol
. 2025 Feb;
53:102311.
PMID: 39922048
Triple-negative breast cancer (TNBC) is the most lethal breast cancer subtype, leading to poor patient outcomes despite aggressive treatment with surgery, radiation, and chemotherapy. There are currently no clinical tests...
2.
Sushentsev N, Hamm G, Flint L, Birtles D, Zakirov A, Richings J, et al.
Nat Commun
. 2024 Jul;
15(1):5980.
PMID: 39013948
Hyperpolarised magnetic resonance imaging (HP-C-MRI) has shown promise as a clinical tool for detecting and characterising prostate cancer. Here we use a range of spatially resolved histological techniques to identify...
3.
Ayyappan V, Jenkinson N, Tressler C, Tan Z, Cheng M, Shen X, et al.
Cell Rep
. 2024 Apr;
43(4):114121.
PMID: 38615320
Metabolic reprogramming is a hallmark of cancer, enabling cancer cells to rapidly proliferate, invade, and metastasize. We show that creatine levels in metastatic breast cancer cell lines and secondary metastatic...
4.
Sushentsev N, Hamm G, Richings J, McLean M, Horvat Menih I, Ayyappan V, et al.
Proc Natl Acad Sci U S A
. 2023 Nov;
120(49):e2312261120.
PMID: 38011568
While radical prostatectomy remains the mainstay of prostate cancer (PCa) treatment, 20 to 40% of patients develop postsurgical biochemical recurrence (BCR). A particularly challenging clinical cohort includes patients with intermediate-risk...
5.
Cai R, Tressler C, Cheng M, Sonkar K, Tan Z, Paidi S, et al.
Sci Rep
. 2023 Oct;
13(1):18566.
PMID: 37903851
The premetastatic niche hypothesis proposes an active priming of the metastatic site by factors secreted from the primary tumor prior to the arrival of the first cancer cells. We investigated...
6.
Tian Y, Ayyappan V, Hemmert K, Myers J, Gitelman Y, Ryskina K
J Hosp Med
. 2023 May;
18(6):524-527.
PMID: 37186454
One-third of patients discharged from hospitals to skilled nursing facilities (SNF) are sent back to the Emergency Department (ED) within 30 days. Little is known about those patients who are...
7.
Boe R, Ayyappan V, Schuh L, Raj A
Cell Syst
. 2022 Nov;
13(12):1016-1032.e6.
PMID: 36450286
Genetic networks should respond to signals but prevent the transmission of spontaneous fluctuations. Limited data from mammalian cells suggest that noise transmission is uncommon, but systematic claims about noise transmission...
8.
Tressler C, Ayyappan V, Nakuchima S, Yang E, Sonkar K, Tan Z, et al.
NMR Biomed
. 2022 May;
36(4):e4770.
PMID: 35538020
NMR spectroscopy and matrix assisted laser desorption ionization mass spectrometry imaging (MALDI MSI) are both commonly used to detect large numbers of metabolites and lipids in metabolomic and lipidomic studies....
9.
Pavuluri K, Yang E, Ayyappan V, Sonkar K, Tan Z, Tressler C, et al.
Theranostics
. 2022 Feb;
12(4):1937-1951.
PMID: 35198081
Chemical exchange saturation transfer (CEST) magnetic resonance imaging (MRI) is emerging as an alternative to gadolinium-based contrast MRI. We have evaluated the possibility of CEST MRI of orthotopic breast tumor...
10.
Scupakova K, Adelaja O, Balluff B, Ayyappan V, Tressler C, Jenkinson N, et al.
JCI Insight
. 2021 Nov;
6(24).
PMID: 34752419
Background: Although aberrant glycosylation is recognized as a hallmark of cancer, glycosylation in clinical breast cancer (BC) metastasis has not yet been studied. While preclinical studies show that the glycocalyx...