Vignesh Shanmugam
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Explore the profile of Vignesh Shanmugam including associated specialties, affiliations and a list of published articles.
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Citations
402
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Recent Articles
1.
Shanmugam V, Tokcan N, Chafamo D, Sullivan S, Borji M, Martin H, et al.
bioRxiv
. 2025 Feb;
PMID: 39896575
A key challenge in cancer research is to identify the secreted factors that contribute to tumor cell survival. Nowhere is this more evident than in Hodgkin lymphoma, where malignant Hodgkin...
2.
Paczkowska J, Tang M, Wright K, Song L, Luu K, Shanmugam V, et al.
Nat Commun
. 2024 Dec;
15(1):10740.
PMID: 39737927
Hodgkin Reed-Sternberg (HRS) cells of classic Hodgkin lymphoma (cHL), like many solid tumors, elicit ineffective immune responses. However, patients with cHL are highly responsive to PD-1 blockade, which largely depends...
3.
Collin M, Gagey G, Shanmugam V, Louissaint Jr A, Okosun J, Sarkozy C, et al.
Histopathology
. 2024 Oct;
86(1):79-93.
PMID: 39468961
Follicular lymphoma (FL) is the second most common type of lymphoma (20% of all non-Hodgkin lymphomas), derived from germinal centre (GC) B cells, and is characterised by its significant clinical,...
4.
Chafamo D, Shanmugam V, Tokcan N
BMC Bioinformatics
. 2024 Oct;
25(1):323.
PMID: 39369208
In the past two decades, genomics has advanced significantly, with single-cell RNA-sequencing (scRNA-seq) marking a pivotal milestone. ScRNA-seq provides unparalleled insights into cellular diversity and has spurred diverse studies across...
5.
Yeo Y, Qiu H, Bai Y, Zhu B, Chang Y, Yeung J, et al.
bioRxiv
. 2024 Mar;
PMID: 38496566
Classic Hodgkin Lymphoma (cHL) is a tumor composed of rare malignant Hodgkin and Reed-Sternberg (HRS) cells nested within a T-cell rich inflammatory immune infiltrate. cHL is associated with Epstein-Barr Virus...
6.
Mata D, Lee J, Shanmugam V, Marcus C, Schrock A, Williams E, et al.
Histopathology
. 2024 Feb;
84(7):1224-1237.
PMID: 38422618
Aims: Liquid biopsy (LBx)-based next-generation sequencing (NGS) of circulating tumour DNA (ctDNA) can facilitate molecular profiling of haematopoietic neoplasms (HNs), particularly when tissue-based NGS is infeasible. Methods And Results: We...
7.
Shaban M, Bai Y, Qiu H, Mao S, Yeung J, Yeo Y, et al.
Nat Commun
. 2024 Jan;
15(1):28.
PMID: 38167832
Highly multiplexed protein imaging is emerging as a potent technique for analyzing protein distribution within cells and tissues in their native context. However, existing cell annotation methods utilizing high-plex spatial...
8.
Russell A, Weir J, Nadaf N, Shabet M, Kumar V, Kambhampati S, et al.
Nature
. 2023 Dec;
625(7994):E11.
PMID: 38110579
No abstract available.
9.
Russell A, Weir J, Nadaf N, Shabet M, Kumar V, Kambhampati S, et al.
Nature
. 2023 Dec;
625(7993):101-109.
PMID: 38093010
Recent technological innovations have enabled the high-throughput quantification of gene expression and epigenetic regulation within individual cells, transforming our understanding of how complex tissues are constructed. However, missing from these...
10.
Sadigh S, DeAngelo D, Garcia J, Hasserjian R, Hergott C, Lane A, et al.
Mod Pathol
. 2023 Oct;
37(1):100352.
PMID: 37839675
In this study, we performed a comprehensive molecular analysis of paired skin and peripheral blood/bone marrow (BM) samples from 17 patients with cutaneous myeloid or cutaneous histiocytic-dendritic neoplasms. The cutaneous...