Victor J Thiruthuvanathan
Overview
Explore the profile of Victor J Thiruthuvanathan including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
61
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0
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Recent Articles
1.
Okoye-Okafor U, Javarappa K, Tsallos D, Saad J, Yang D, Zhang C, et al.
J Exp Med
. 2022 Sep;
219(11).
PMID: 36053753
Thrombocytopenia, prevalent in the majority of patients with myeloid malignancies, such as myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML), is an independent adverse prognostic factor. Azacitidine (AZA), a mainstay...
2.
Aivalioti M, Bartholdy B, Pradhan K, Bhagat T, Zintiridou A, Jeong J, et al.
Blood Cancer Discov
. 2022 Jul;
3(5):444-467.
PMID: 35820129
Significance: We identify moderately impaired PU.1 mRNA expression as a biological modality predisposing Tet2-deficient hematopoietic stem and progenitor cells to malignant transformation. Our study furthermore uncovers a methylation-sensitive PU.1 gene...
3.
Shastri A, Choudhary G, Teixeira M, Gordon-Mitchell S, Ramachandra N, Bernard L, et al.
J Clin Invest
. 2018 Sep;
128(12):5479-5488.
PMID: 30252677
Acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS) are associated with disease-initiating stem cells that are not eliminated by conventional therapies. Transcriptomic analysis of stem and progenitor populations in MDS...