Victor J Chen
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Explore the profile of Victor J Chen including associated specialties, affiliations and a list of published articles.
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12
Citations
481
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Recent Articles
1.
Smith G, Esson J, Chen V, Hanson R
Forensic Sci Int Synerg
. 2020 Dec;
3:100130.
PMID: 33354665
The use of forensic dye analysis in the field of cultural heritage is introduced, and a case study is presented determining the dating of a potentially important textile fragment from...
2.
Calvo E, Chen V, Marshall M, Ohnmacht U, Hynes S, Kumm E, et al.
Invest New Drugs
. 2014 Jun;
32(5):955-68.
PMID: 24942404
LY2603618 is an inhibitor of checkpoint kinase 1 (CHK1), an important regulator of the DNA damage checkpoints. Preclinical experiments analyzed NCI-H2122 and NCI-H441 NSCLC cell lines and in vitro/in vivo...
3.
Abdel-Karim I, Plunkett Jr W, OBrien S, Giles F, Thomas D, Faderl S, et al.
Invest New Drugs
. 2010 Jan;
29(2):323-31.
PMID: 20091088
Purpose: To investigate the toxicity profile, activity, pharmacokinetics, and pharmacodynamics of pemetrexed in leukemia. Patients And Methods: Patients with refractory or relapsed acute leukemia were eligible. A phase I 3+3...
4.
Woo K, Chen V, Jung H, Kim T, Shin H, Baek J, et al.
Tissue Eng Part A
. 2009 Apr;
15(8):2155-62.
PMID: 19348597
In a previous study we found that nanofibrous poly(l-lactic acid) (PLLA) scaffolds mimicking collagen fibers in size were superior to solid-walled scaffolds in promoting osteoblast differentiation and bone formation in...
5.
Dotzlaf J, Carpenter J, Luo S, Miles R, Fisher D, Qian Y, et al.
Hybridoma (Larchmt)
. 2007 Jun;
26(3):155-61.
PMID: 17600497
Folypolyglutamate synthetase (FPGS) plays a critical role in the cellular retention of both folates and antifolates. Resistance to antifolates is in part related to changes in FPGS enzyme activity and...
6.
Woo K, Jun J, Chen V, Seo J, Baek J, Ryoo H, et al.
Biomaterials
. 2006 Jul;
28(2):335-43.
PMID: 16854461
Nano-fibrous poly(L-lactic acid) (PLLA) scaffolds with interconnected pores were developed under the hypothesis that nano-fibrous scaffolding would mimic a morphological function of collagen fibrils to create a more favorable microenvironment...
7.
Dotzlaf J, Carpenter J, Luo S, Roberts E, Solenberg P, Qian Y, et al.
Hybridoma (Larchmt)
. 2006 Jun;
25(3):139-44.
PMID: 16796460
Glycinamide ribonucleotide formyltransferase (GARFT) is a trifunctional enzyme involved in purine biosynthesis. Its central role in folate metabolism has made it an obvious target for the development of GARFT inhibitors,...
8.
Chen V, Smith L, Ma P
Biomaterials
. 2006 Mar;
27(21):3973-9.
PMID: 16564086
The ability to control architectural features in tissue engineering scaffolds is critical to the success of neo-tissue regeneration. In this work, reverse solid freeform fabrication and thermal phase separation of...
9.
Chen V, Ma P
Biomaterials
. 2006 Mar;
27(20):3708-15.
PMID: 16519935
In vitro hydrolytic degradation behavior was examined for nano-fibrous (NF) poly(L-lactic acid) (PLLA) foams prepared by phase separation. NF foams were incubated in phosphate-buffered saline at 37 degrees C for...
10.
Gomez H, Santillana S, Vallejos C, Velarde R, Sanchez J, Wang X, et al.
Clin Cancer Res
. 2006 Feb;
12(3 Pt 1):832-8.
PMID: 16467096
Purpose: This phase II trial of pemetrexed explored potential correlations between treatment outcome (antitumor activity) and molecular target expression. Experimental Design: Chemonaïve patients with advanced breast cancer received up to...