Vibha Tandon
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Explore the profile of Vibha Tandon including associated specialties, affiliations and a list of published articles.
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76
Citations
559
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Recent Articles
1.
Cardoza S, Singh A, Sur S, Singh M, Dubey K, Samanta S, et al.
Heliyon
. 2024 Sep;
10(17):e36786.
PMID: 39286185
Remdesivir, a C-nucleotide prodrug binds to the viral RNA-dependent-RNA polymerase () and inhibits the viral replication by terminating RNA transcription prematurely. It is reported in literature that interaction between the...
2.
Lokhande A, Maurya V, Rani K, Parashar P, Gaind R, Tandon V, et al.
Int J Pharm
. 2024 Mar;
655:123982.
PMID: 38460770
Recently, World Health Organization declared antimicrobial resistance as the third greatest threat to human health. Absence of known cross-resistance, new class, new target, and a new mode of action are...
3.
Rana M, Hungyo H, Parashar P, Ahmad S, Mehandi R, Tandon V, et al.
RSC Adv
. 2023 Sep;
13(38):26766-26779.
PMID: 37681049
We have designed and synthesized three pyrazole analogs (4, 5a, 5b), pyrazole-based chalcones (6a-6d) and (8a-8h), and -formyl/acetyl 1,3,5-trisubstituted pyrazoline analogs (7a-7d), (9a-9d). FT-IR, H, C NMR, and mass spectrometry...
4.
Chaudhari T, Bisht S, Chorol S, Bhujbal S, Bharatam P, Tandon V
J Org Chem
. 2023 Jul;
88(15):10412-10425.
PMID: 37440673
A regioselective direct carboxamidation reaction of 2-indolylmethanols with readily available isocyanoesters/isocyanides has been reported in this work. The reaction was catalyzed by Bronsted acid such as -TsOH to deliver the...
5.
Cardoza S, Shrivash M, Riva L, Chatterjee A, Mandal A, Tandon V
J Org Chem
. 2023 Jun;
88(13):9105-9122.
PMID: 37276453
Studies suggest that the 1'β-CN moiety in remdesivir sterically clashes with the Ser861 residue of the RNA-dependent-RNA polymerase (RdRp), causing a delayed chain termination in the RNA replication process. Replacing...
6.
Cardoza S, Yadav P, Ajmani A, Das P, Tandon V
ACS Omega
. 2023 Mar;
8(9):8415-8426.
PMID: 36910947
There is a continuing demand of new inhibitors of HIV-1 Integrase (HIV-1 IN) due to mutations of HIV-1. This study aims to develop the synthesis of 3,6-diaryl 7-azaindoles and introspect...
7.
Maurya V, Singh R, Singh R, Pandey S, Yadav P, Parashar P, et al.
Commun Biol
. 2023 Feb;
6(1):195.
PMID: 36807602
Type IA topoisomerases maintain DNA topology by cleaving ssDNA and relaxing negative supercoils. The inhibition of its activity in bacteria prevents the relaxation of negative supercoils, which in turn impedes...
8.
Sharma T, Kundu N, Kaur S, Tandon V, Shankaraswamy J, Saxena S
J Biomol Struct Dyn
. 2022 Nov;
41(19):9977-9986.
PMID: 36437795
Human telomeric DNA can fold into G-quadruplex structures involving the interaction of four guanine bases in a square planar arrangement. The highly distinctive nature of quadruplex topologies suggests that they...
9.
Singh A, Rani K, Tandon V, Sahoo A, Samanta S
Biomater Sci
. 2022 Oct;
10(23):6778-6790.
PMID: 36314248
Biofilm infections are highly resistant to commercial antibiotics. Therefore, developing a potent agent against such drug-resistant bacterial infections is highly desirable. Here, we synthesized positively charged silver nanoclusters (Ag NCs)...
10.
Parashar P, Das M, Tripathi P, Kataria T, Gupta D, Sarin D, et al.
Cancers (Basel)
. 2022 Oct;
14(19).
PMID: 36230831
Survival, recurrence, and xerostomia are considerable problems in the treatment of oral squamous carcinoma patients. In this study, we investigated the role of DMA (5-(4-methylpiperazin-1-yl)-2-[2'-(3,4-dimethoxyphenyl)5″benzimidazoyl]benzimidazole) as a salivary gland cytoprotectant...