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Venugopalan D Nair

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Articles 46
Citations 1020
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Recent Articles
11.
Mao W, Miller C, Nair V, Ge Y, Amper M, Cappuccio A, et al.
Mol Syst Biol . 2023 Mar; 19(5):e11361. PMID: 36919946
DNA methylation comprises a cumulative record of lifetime exposures superimposed on genetically determined markers. Little is known about methylation dynamics in humans following an acute perturbation, such as infection. We...
12.
Smith G, Zhao B, Lindholm M, Raja A, Viggars M, Pincas H, et al.
bioRxiv . 2023 Jan; PMID: 36711841
Transcription factors (TFs) play a key role in regulating gene expression and responses to stimuli. We conducted an integrated analysis of chromatin accessibility, DNA methylation, and RNA expression across eight...
13.
Aydillo T, Gonzalez-Reiche A, Stadlbauer D, Amper M, Nair V, Mariottini C, et al.
NPJ Vaccines . 2022 Dec; 7(1):160. PMID: 36496417
A phase 1 clinical trial to test the immunogenicity of a chimeric group 1 HA (cHA) universal influenza virus vaccine targeting the conserved stalk domain of the hemagglutinin of influenza...
14.
Sauerwald N, Zhang Z, Ramos I, Nair V, Soares-Schanoski A, Ge Y, et al.
Cell Syst . 2022 Nov; 13(11):924-931.e4. PMID: 36323307
Male sex is a major risk factor for SARS-CoV-2 infection severity. To understand the basis for this sex difference, we studied SARS-CoV-2 infection in a young adult cohort of United...
15.
Lizewski R, Sealfon R, Park S, Smith G, Porter C, Gonzalez-Reiche A, et al.
Epidemiology . 2022 Aug; 33(6):797-807. PMID: 35944149
Background: Marine recruits training at Parris Island experienced an unexpectedly high rate of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, despite preventive measures including a supervised, 2-week, pre-entry quarantine....
16.
Cappuccio A, Geis J, Ge Y, Nair V, Ramalingam N, Mao W, et al.
Clin Transl Discov . 2022 Aug; 2(3):e47. PMID: 35942160
No abstract available.
17.
Mendelev N, Zamojski M, Amper M, Cheng W, Pincas H, Nair V, et al.
STAR Protoc . 2022 Jun; 3(2):101446. PMID: 35693209
Concomitant profiling of transcriptome and chromatin accessibility in isolated nuclei can reveal gene regulatory control mechanisms in health and disease. We report a single nucleus multi-omics analysis protocol optimized for...
18.
Soares-Schanoski A, Sauerwald N, Goforth C, Periasamy S, Weir D, Lizewski S, et al.
Front Immunol . 2022 Apr; 13:821730. PMID: 35479098
Young adults infected with SARS-CoV-2 are frequently asymptomatic or develop only mild disease. Because capturing representative mild and asymptomatic cases require active surveillance, they are less characterized than moderate or...
19.
Nair V, Vasoya M, Nair V, Smith G, Pincas H, Ge Y, et al.
MethodsX . 2022 Apr; 9:101681. PMID: 35464805
ATAC-seq is a fast and sensitive method for the epigenomic profiling of open chromatin and for mapping of transcription factor binding sites [1]. Despite the development of the Omni-ATAC protocol...
20.
Zhang Z, Zamojski M, Smith G, Willis T, Yianni V, Mendelev N, et al.
Cell Rep . 2022 Mar; 38(10):110467. PMID: 35263594
Despite their importance in tissue homeostasis and renewal, human pituitary stem cells (PSCs) are incompletely characterized. We describe a human single nucleus RNA-seq and ATAC-seq resource from pediatric, adult, and...