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Vasuretha Chandar

Explore the profile of Vasuretha Chandar including associated specialties, affiliations and a list of published articles. Areas
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Articles 28
Citations 1419
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Recent Articles
1.
Yang L, Kim T, Han Y, Nair M, Harschnitz O, Zhu J, et al.
Cell Stem Cell . 2024 Jan; 31(2):196-211.e6. PMID: 38237586
COVID-19 patients commonly present with signs of central nervous system and/or peripheral nervous system dysfunction. Here, we show that midbrain dopamine (DA) neurons derived from human pluripotent stem cells (hPSCs)...
2.
Liu Y, Cafiero T, Park D, Biswas A, Winer B, Cho C, et al.
Nat Commun . 2023 Jun; 14(1):3582. PMID: 37328459
Hepatitis B virus (HBV) only infects humans and chimpanzees, posing major challenges for modeling HBV infection and chronic viral hepatitis. The major barrier in establishing HBV infection in non-human primates...
3.
Bram Y, Duan X, Nilsson-Payant B, Chandar V, Wu H, Shore D, et al.
ACS Bio Med Chem Au . 2022 Dec; 2(6):627-641. PMID: 36570071
The SARS-CoV-2 pandemic is an ongoing threat to global health, and the continuing emergence of contagious variants highlights the urgent need for additional antiviral therapy to attenuate COVID-19 disease. The...
4.
Laurent P, Yang C, Rendeiro A, Nilsson-Payant B, Carrau L, Chandar V, et al.
Sci Immunol . 2022 Sep; 7(75):eadd4906. PMID: 36083891
Lung-infiltrating macrophages create a marked inflammatory milieu in a subset of patients with COVID-19 by producing a cytokine storm, which correlates with increased lethality. However, these macrophages are largely not...
5.
Liu Y, Park D, Cafiero T, Bram Y, Chandar V, Tseng A, et al.
JHEP Rep . 2022 Aug; 4(9):100535. PMID: 36035359
Background & Aims: HBV exhibits wide genetic diversity with at least 9 genotypes (GTs), which differ in terms of prevalence, geographic distribution, natural history, disease progression, and treatment outcome. However,...
6.
Frere J, Serafini R, Pryce K, Zazhytska M, Oishi K, Golynker I, et al.
Sci Transl Med . 2022 Jul; 14(664):eabq3059. PMID: 35857629
The host response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can result in prolonged pathologies collectively referred to as post-acute sequalae of COVID-19 (PASC) or long COVID. To...
7.
Batlle D, Monteil V, Garreta E, Hassler L, Wysocki J, Chandar V, et al.
Cell . 2022 May; 185(11):1837-1839. PMID: 35623327
No abstract available.
8.
Argueta L, Lacko L, Bram Y, Tada T, Carrau L, Rendeiro A, et al.
iScience . 2022 Apr; 25(5):104223. PMID: 35434541
The effect of SARS-CoV-2 infection on placental function is not well understood. Analysis of placentas from women who tested positive at delivery showed SARS-CoV-2 genomic and subgenomic RNA in 22...
9.
Kastenhuber E, Mercadante M, Nilsson-Payant B, Johnson J, Jaimes J, Muecksch F, et al.
Elife . 2022 Mar; 11. PMID: 35294338
Coagulopathy is a significant aspect of morbidity in COVID-19 patients. The clotting cascade is propagated by a series of proteases, including factor Xa and thrombin. While certain host proteases, including...
10.
Park J, Foox J, Hether T, Danko D, Warren S, Kim Y, et al.
Cell Rep Med . 2022 Mar; 3(2):100522. PMID: 35233546
The molecular mechanisms underlying the clinical manifestations of coronavirus disease 2019 (COVID-19), and what distinguishes them from common seasonal influenza virus and other lung injury states such as acute respiratory...