Vasudeva Ginjala
Overview
Explore the profile of Vasudeva Ginjala including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
518
Followers
0
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Recent Articles
1.
Simhadri S, Carrick J, Murphy S, Kothari O, Al-Hraishami H, Kulkarni A, et al.
JCO Precis Oncol
. 2024 Dec;
8:e2300260.
PMID: 39626159
Purpose: Combined BRAF, MEK, and EGFR inhibition can induce clinical responses in BRAF-V600E-mutant colon cancer, but rapid resistance often occurs. Methods: We use serial monitoring of circulating tumor DNA cell-free...
2.
Kang Z, Fu P, Ma H, Li T, Lu K, Liu J, et al.
bioRxiv
. 2023 Oct;
PMID: 37873068
EHTM1 (GLP) and EHMT2 (G9a) are closely related protein lysine methyltransferases often thought to function together as a heterodimer to methylate histone H3 and non-histone substrates in diverse cellular processes...
3.
Ginjala V, Rodriguez-Colon L, Ganguly B, Gangidi P, Gallina P, Al-Hraishawi H, et al.
Sci Rep
. 2017 Dec;
7(1):16613.
PMID: 29192276
Upon induction of DNA breaks, ATM activation leads to a cascade of local chromatin modifications that promote efficient recruitment of DNA repair proteins. Errors in this DNA repair pathway lead...
4.
Ramdzan Z, Ginjala V, Pinder J, Chung D, Donovan C, Kaur S, et al.
Oncotarget
. 2017 Feb;
8(12):19021-19038.
PMID: 28147323
Ionizing radiation generates a broad spectrum of oxidative DNA lesions, including oxidized base products, abasic sites, single-strand breaks and double-strand breaks. The CUX1 protein was recently shown to function as...
5.
Oza J, Ganguly B, Kulkarni A, Ginjala V, Yao M, Ganesan S
J Biol Chem
. 2017 Jan;
292(2):761.
PMID: 28087730
No abstract available.
6.
Oza J, Ganguly B, Kulkarni A, Ginjala V, Yao M, Ganesan S
J Biol Chem
. 2016 Aug;
291(44):22881-22893.
PMID: 27555324
Induction of DNA damage induces a dynamic repair process involving DNA repair factors and epigenetic regulators. Chromatin alterations must occur for DNA repair factors to gain access to DNA lesions...
7.
Kulkarni A, Oza J, Yao M, Sohail H, Ginjala V, Tomas-Loba A, et al.
J Biol Chem
. 2013 Aug;
288(45):32357-32369.
PMID: 23926104
Activation of poly(ADP-ribose) polymerase (PARP) near sites of DNA breaks facilitates recruitment of DNA repair proteins and promotes chromatin relaxation in part through the action of chromatin-remodeling enzyme Amplified in...
8.
Nacerddine K, Beaudry J, Ginjala V, Westerman B, Mattiroli F, Song J, et al.
J Clin Invest
. 2012 Apr;
122(5):1920-32.
PMID: 22505453
Prostate cancer (PCa) is a major lethal malignancy in men, but the molecular events and their interplay underlying prostate carcinogenesis remain poorly understood. Epigenetic events and the upregulation of polycomb...
9.
Bilal E, Alexe G, Yao M, Cong L, Kulkarni A, Ginjala V, et al.
Genes Cancer
. 2011 Jul;
1(10):1063-73.
PMID: 21779430
Normal cellular behavior can be described as a complex, regulated network of interaction between genes and proteins. Targeted cancer therapies aim to neutralize specific proteins that are necessary for the...
10.
Ginjala V, Nacerddine K, Kulkarni A, Oza J, Hill S, Yao M, et al.
Mol Cell Biol
. 2011 Mar;
31(10):1972-82.
PMID: 21383063
DNA damage activates signaling pathways that lead to modification of local chromatin and recruitment of DNA repair proteins. Multiple DNA repair proteins having ubiquitin ligase activity are recruited to sites...