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Vanessa van Harmelen

Explore the profile of Vanessa van Harmelen including associated specialties, affiliations and a list of published articles. Areas
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Articles 52
Citations 1656
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Recent Articles
1.
Katiraei S, Anvar Y, Hoving L, Berbee J, van Harmelen V, Willems van Dijk K
Curr Microbiol . 2022 Jul; 79(9):276. PMID: 35907023
The composition of microbial communities is commonly determined by sequence analyses of one of the variable (V) regions in the bacterial 16S rRNA gene. We aimed to assess whether sequencing...
2.
Katiraei S, van Diepen J, Tavares L, Hoving L, Pronk A, Verschueren I, et al.
Sci Rep . 2022 Apr; 12(1):6883. PMID: 35477719
Bone marrow transplantation (BMT) involves conditioning regimens which acutely induce side effects, including systemic inflammation, intestinal damage and shifts in the gut microbial composition, some of which may persist chronically....
3.
In Het Panhuis W, Tsaalbi-Shtylik A, Schonke M, van Harmelen V, Pronk A, Streefland T, et al.
Am J Physiol Endocrinol Metab . 2022 Feb; 322(3):E319-E329. PMID: 35156394
DNA damage responses compete for cellular resources with metabolic pathways, but little is known about the metabolic consequences of impaired DNA replication, a process called replication stress. Here we characterized...
4.
Embgenbroich M, van der Zande H, Hussaarts L, Schulte-Schrepping J, Pelgrom L, Garcia-Tardon N, et al.
Proc Natl Acad Sci U S A . 2021 Jul; 118(31). PMID: 34326259
Proinflammatory activation of macrophages in metabolic tissues is critically important in the induction of obesity-induced metaflammation. Here, we demonstrate that the soluble mannose receptor (sMR) plays a direct functional role...
5.
Katiraei S, de Vries M, Costain A, Thiem K, Hoving L, van Diepen J, et al.
Mol Nutr Food Res . 2019 Aug; 64(15):e1900732. PMID: 31389129
Scope: Akkermansia muciniphila (A. muciniphila) is an intestinal commensal with anti-inflammatory properties both in the intestine and other organs. The aim is to investigate the effects of oral administration of...
6.
Nahon J, Hoekstra M, van Harmelen V, Rensen P, Willems van Dijk K, Kooijman S, et al.
Biochim Biophys Acta Mol Basis Dis . 2018 Nov; 1865(2):494-501. PMID: 30448542
Objective: Proteoglycan 4 (Prg4) has emerged from human association studies as a possible factor contributing to weight gain, dyslipidemia and insulin resistance. In the current study, we investigated the causal...
7.
Hoving L, Katiraei S, Pronk A, Heijink M, Vonk K, Amghar-El Bouazzaoui F, et al.
Sci Rep . 2018 Nov; 8(1):16515. PMID: 30409998
Gut microbiota have been implicated in the development of atherosclerosis and cardiovascular disease. Since the prebiotic inulin is thought to beneficially affect gut microbiota, we aimed to determine the effect...
8.
Hoving L, van der Zande H, Pronk A, Guigas B, Willems van Dijk K, van Harmelen V
PLoS One . 2018 May; 13(5):e0196165. PMID: 29723205
The indigestible mannan oligosaccharides (MOS) derived from the outer cell wall of yeast Saccharomyces cerevisiae have shown potential to reduce inflammation. Since inflammation is one of the underlying mechanisms involved...
9.
Hoving L, Katiraei S, Heijink M, Pronk A, van der Wee-Pals L, Streefland T, et al.
Mol Nutr Food Res . 2018 Apr; 62(10):e1700942. PMID: 29665623
Scope: Mannan oligosaccharides (MOS) have proven effective at improving growth performance, while also reducing hyperlipidemia and inflammation. As atherosclerosis is accelerated both by hyperlipidemia and inflammation, we aim to determine...
10.
Fransen M, Benonisson H, van Maren W, Sow H, Breukel C, Linssen M, et al.
J Immunol . 2018 Mar; 200(8):2615-2626. PMID: 29523656
By their interaction with IgG immune complexes, FcγR and complement link innate and adaptive immunity, showing functional redundancy. In complement-deficient mice, IgG downstream effector functions are often impaired, as well...