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Vanessa Rodrik

Explore the profile of Vanessa Rodrik including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 234
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Recent Articles
1.
OReilly K, Warycha M, Davies M, Rodrik V, Zhou X, Yee H, et al.
Clin Cancer Res . 2009 Apr; 15(8):2872-8. PMID: 19336517
Purpose: Both phosphatidylinositol 3-kinase/AKT and RAS/mitogen-activated protein kinase signal transduction pathways mediate 4E-BP1 phosphorylation, releasing 4E-BP1 from the mRNA cap and permitting translation initiation. Given the prevalence of PTEN and...
2.
Rodrik V, Gomes E, Hui L, Rockwell P, Foster D
FEBS Lett . 2006 Sep; 580(24):5647-52. PMID: 16996503
Estrogen, which has been strongly implicated in breast cancer, suppresses apoptosis in estrogen receptor (ER) positive MCF-7 breast cancer cells. Phospholipase D (PLD), which is commonly elevated in ER negative...
3.
Zheng Y, Rodrik V, Toschi A, Shi M, Hui L, Shen Y, et al.
J Biol Chem . 2006 Apr; 281(23):15862-8. PMID: 16595654
MDA-MB-231 human breast cancer cells belong to a highly invasive metastatic cell line that depends on phospholipase D (PLD) activity for survival when deprived of serum growth factors. In response...
4.
Hui L, Rodrik V, Pielak R, Knirr S, Zheng Y, Foster D
J Biol Chem . 2005 Aug; 280(43):35829-35. PMID: 16109716
A critical aspect of tumor progression is the generation of survival signals that overcome default apoptotic programs. Recent studies have revealed that elevated phospholipase D activity generates survival signals in...
5.
Rodrik V, Zheng Y, Harrow F, Chen Y, Foster D
Mol Cell Biol . 2005 Aug; 25(17):7917-25. PMID: 16107734
Estrogens, which have been strongly implicated in the development of breast cancer, enhance proliferation of mammary epithelial cells and, importantly, estrogen receptor (ER)-positive breast cancer cells. In the absence of...
6.
Chen Y, Rodrik V, Foster D
Oncogene . 2004 Dec; 24(4):672-9. PMID: 15580312
Cancer cells generate survival signals to suppress default apoptotic programs that protect from cancer. Phosphatidylinositol-3-kinase (PI3K) generates a survival signal that is frequently dysregulated in human cancers. Phospholipase D (PLD)...