Vanessa Chenouard
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Explore the profile of Vanessa Chenouard including associated specialties, affiliations and a list of published articles.
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14
Citations
291
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Recent Articles
1.
Chenouard V, Leray I, Tesson L, Remy S, Allan A, Archer D, et al.
iScience
. 2023 Apr;
26(4):106399.
PMID: 37034986
CRISPR-Cas9 cleavage efficacy and accuracy are the main challenges gene editing faces, and they are particularly affected by the optimal formation of the ribonucleoprotein (RNP) complex. We used nano differential...
2.
CD4 and CD8 regulatory T cell characterization in the rat using a unique transgenic Foxp3-EGFP model
Menoret S, Tesson L, Remy S, Gourain V, Serazin C, Usal C, et al.
BMC Biol
. 2023 Jan;
21(1):8.
PMID: 36635667
Background: Regulatory T cells (Treg) in diverse species include CD4 and CD8 T cells. In all species, CD8 Treg have been only partially characterized and there is no rat model...
3.
Crispo M, Chenouard V, Dos Santos-Neto P, Tesson L, Souza-Neves M, Heslan J, et al.
Methods Mol Biol
. 2022 Jun;
2495:233-244.
PMID: 35696036
CRISPR/Cas9 system is a promising method for the generation of human disease models by genome editing in non-conventional experimental animals. Medium/large-sized animals like sheep have several advantages to study human...
4.
Chenouard V, Remy S, Tesson L, Menoret S, Ouisse L, Cherifi Y, et al.
Front Genet
. 2021 May;
12:615491.
PMID: 33959146
The rat has been extensively used as a small animal model. Many genetically engineered rat models have emerged in the last two decades, and the advent of gene-specific nucleases has...
5.
Menoret S, Ouisse L, Tesson L, Remy S, Usal C, Guiffes A, et al.
Transplantation
. 2019 Nov;
104(4):715-723.
PMID: 31764762
Background: Humanized immune system immunodeficient mice have been extremely useful for the in vivo analyses of immune responses in a variety of models, including organ transplantation and graft versus host...
6.
Ouisse L, Remy S, Lafoux A, Larcher T, Tesson L, Chenouard V, et al.
Front Immunol
. 2019 Sep;
10:2131.
PMID: 31552055
Corticosteroids (CS) are standard therapy for the treatment of Duchenne's muscular dystrophy (DMD). Even though they decrease inflammation, they have limited efficacy and are associated with significant side effects. There...
7.
Menoret S, Ouisse L, Tesson L, Delbos F, Garnier D, Remy S, et al.
Transplantation
. 2018 Apr;
102(8):1271-1278.
PMID: 29688994
Background: Immunodeficient mice are invaluable tools to analyze the long-term effects of potentially immunogenic molecules in the absence of adaptive immune responses. Nevertheless, there are models and experimental situations that...
8.
Remy S, Chenouard V, Tesson L, Usal C, Menoret S, Brusselle L, et al.
Sci Rep
. 2017 Nov;
7(1):16554.
PMID: 29185448
The generation of gene-edited animals using the CRISPRs/Cas9 system is based on microinjection into zygotes which is inefficient, time consuming and demands high technical skills. We report the optimization of...
9.
Menoret S, Tesson L, Remy S, Usal C, Ouisse L, Brusselle L, et al.
Transgenic Res
. 2017 Aug;
26(5):703-708.
PMID: 28780744
On May 11th and 12th 2017 was held in Nantes, France, the international meeting "Advances in transgenic animal models and techniques" ( http://www.trm.univ-nantes.fr/ ). This biennial meeting is the fifth...
10.
Jung C, Menoret S, Brusselle L, Tesson L, Usal C, Chenouard V, et al.
Sci Rep
. 2016 Aug;
6:31455.
PMID: 27530248
BAC transgenic mammalian systems offer an important platform for recapitulating human gene expression and disease modeling. While the larger body mass, and greater genetic and physiologic similarity to humans render...