Lucas Brusselle
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Explore the profile of Lucas Brusselle including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
160
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Recent Articles
1.
Cardon A, Guinebretiere T, Dong C, Gil L, Ado S, Gavlovsky P, et al.
Nat Commun
. 2025 Jan;
16(1):1161.
PMID: 39880819
Autoimmune liver diseases (AILD) involve dysregulated CD4 T cell responses against liver self-antigens, but how these autoreactive T cells relate to liver tissue pathology remains unclear. Here we perform single-cell...
2.
Ouisse L, Remy S, Lafoux A, Larcher T, Tesson L, Chenouard V, et al.
Front Immunol
. 2019 Sep;
10:2131.
PMID: 31552055
Corticosteroids (CS) are standard therapy for the treatment of Duchenne's muscular dystrophy (DMD). Even though they decrease inflammation, they have limited efficacy and are associated with significant side effects. There...
3.
Menoret S, Ouisse L, Tesson L, Delbos F, Garnier D, Remy S, et al.
Transplantation
. 2018 Apr;
102(8):1271-1278.
PMID: 29688994
Background: Immunodeficient mice are invaluable tools to analyze the long-term effects of potentially immunogenic molecules in the absence of adaptive immune responses. Nevertheless, there are models and experimental situations that...
4.
Remy S, Chenouard V, Tesson L, Usal C, Menoret S, Brusselle L, et al.
Sci Rep
. 2017 Nov;
7(1):16554.
PMID: 29185448
The generation of gene-edited animals using the CRISPRs/Cas9 system is based on microinjection into zygotes which is inefficient, time consuming and demands high technical skills. We report the optimization of...
5.
Menoret S, Tesson L, Remy S, Usal C, Ouisse L, Brusselle L, et al.
Transgenic Res
. 2017 Aug;
26(5):703-708.
PMID: 28780744
On May 11th and 12th 2017 was held in Nantes, France, the international meeting "Advances in transgenic animal models and techniques" ( http://www.trm.univ-nantes.fr/ ). This biennial meeting is the fifth...
6.
Jung C, Menoret S, Brusselle L, Tesson L, Usal C, Chenouard V, et al.
Sci Rep
. 2016 Aug;
6:31455.
PMID: 27530248
BAC transgenic mammalian systems offer an important platform for recapitulating human gene expression and disease modeling. While the larger body mass, and greater genetic and physiologic similarity to humans render...
7.
Chenouard V, Brusselle L, Heslan J, Remy S, Menoret S, Usal C, et al.
J Genet Genomics
. 2016 May;
43(5):341-8.
PMID: 27209567
The recent emergence and application of engineered endonucleases have led to the development of genome editing tools capable of rapidly implementing various targeted genome editions in a wide range of...
8.
Menoret S, De Cian A, Tesson L, Remy S, Usal C, Boule J, et al.
Sci Rep
. 2015 Oct;
5:14410.
PMID: 26442875
The generation of genetically-modified organisms has been revolutionized by the development of new genome editing technologies based on the use of gene-specific nucleases, such as meganucleases, ZFNs, TALENs and CRISPRs-Cas9...
9.
Menoret S, Tesson L, Remy S, Usal C, Ouisse L, Brusselle L, et al.
Transgenic Res
. 2015 Sep;
24(6):1079-85.
PMID: 26358113
No abstract available.