Valerio Costa
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Explore the profile of Valerio Costa including associated specialties, affiliations and a list of published articles.
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Articles
58
Citations
1122
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Recent Articles
21.
Aprile M, Cataldi S, Ambrosio M, DEsposito V, Lim K, Dietrich A, et al.
Cell Rep
. 2018 Nov;
25(6):1577-1592.e6.
PMID: 30404011
Peroxisome-proliferator-activated receptor γ (PPARγ) regulates glucose and lipid homeostasis, insulin signaling, and adipocyte differentiation. Here, we report the skipping of exon 5 as a legitimate splicing event generating PPARγΔ5, a...
22.
Petrizzo A, Tagliamonte M, Mauriello A, Costa V, Aprile M, Esposito R, et al.
J Transl Med
. 2018 Oct;
16(1):286.
PMID: 30340600
Background: A novel prediction algorithm is needed for the identification of effective tumor associated mutated neoantigens. Only those with no homology to self wild type antigens are true predicted neoantigens...
23.
Li J, Deng S, Vieira J, Thomas J, Costa V, Tseng C, et al.
Database (Oxford)
. 2018 Jun;
2018.
PMID: 29931156
RNA-binding proteins (RBPs) may play a critical role in gene regulation in various diseases or biological processes by controlling post-transcriptional events such as polyadenylation, splicing and mRNA stabilization via binding...
24.
De Gregorio R, Pulcrano S, De Sanctis C, Volpicelli F, Guatteo E, Von Oerthel L, et al.
Stem Cell Reports
. 2018 Mar;
10(4):1237-1250.
PMID: 29526736
The differentiation of dopaminergic neurons requires concerted action of morphogens and transcription factors acting in a precise and well-defined time window. Very little is known about the potential role of...
25.
Ambrosio M, DEsposito V, Costa V, Liguoro D, Collina F, Cantile M, et al.
Oncotarget
. 2018 Jan;
8(65):109000-109017.
PMID: 29312586
Type 2 diabetes and obesity are negative prognostic factors in patients with breast cancer (BC). We found that sensitivity to tamoxifen was reduced by 2-fold by 25 mM glucose (High...
26.
Terracciano D, Terreri S, de Nigris F, Costa V, Calin G, Cimmino A
Biochim Biophys Acta Rev Cancer
. 2017 Sep;
1868(2):449-455.
PMID: 28916343
Ultraconserved regions (UCRs) represent a relatively new class of non-coding genomic sequences highly conserved between human, rat and mouse genomes. These regions can reside within exons of protein-coding genes, despite...
27.
Schiano C, Costa V, Aprile M, Grimaldi V, Maiello C, Esposito R, et al.
Cardiol J
. 2017 May;
24(5):539-553.
PMID: 28497843
Background: Despite left ventricular (LV) dysfunction contributing to mortality in chronic heart failure (HF), the molecular mechanisms of LV failure continues to remain poorly understood and myocardial biomarkers have yet...
28.
Federico A, Rienzo M, Abbondanza C, Costa V, Ciccodicola A, Casamassimi A
Int J Mol Sci
. 2017 May;
18(5).
PMID: 28468258
The integrator complex has been recently identified as a key regulator of RNA Polymerase II-mediated transcription, with many functions including the processing of small nuclear RNAs, the pause-release and elongation...
29.
Costa V, Righelli D, Russo F, De Berardinis P, Angelini C, DApice L
Int J Mol Sci
. 2017 Mar;
18(3).
PMID: 28245601
Vaccination is the most successful and cost-effective method to prevent infectious diseases. However, many vaccine antigens have poor in vivo immunogenic potential and need adjuvants to enhance immune response. The...
30.
Trovato M, Maurano F, DApice L, Costa V, Sartorius R, Cuccaro F, et al.
BMC Microbiol
. 2016 Jul;
16(1):152.
PMID: 27421762
Background: The E2 multimeric scaffold represents a powerful delivery system able to elicit robust humoral and cellular immune responses upon systemic administrations. Here recombinant E2 scaffold displaying the third variable...