Valerie Vingtdeux
Overview
Explore the profile of Valerie Vingtdeux including associated specialties, affiliations and a list of published articles.
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45
Citations
2488
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Recent Articles
1.
Nebie O, Devos D, Vingtdeux V, Barro L, Devedjian J, Jonneaux A, et al.
J Biomed Sci
. 2019 Nov;
26(1):89.
PMID: 31666073
Background: Effective neurorestorative therapies of neurodegenerative diseases must be developed. There is increasing interest in using human platelet lysates, rich in neurotrophic factors, as novel disease-modifying strategy of neurodegeneration. To...
2.
Sergeant N, Vingtdeux V, Eddarkaoui S, Gay M, Evrard C, Le Fur N, et al.
Neurobiol Dis
. 2019 Apr;
129:217-233.
PMID: 30928644
Alzheimer's Disease is a devastating dementing disease involving amyloid deposits, neurofibrillary tangles, progressive and irreversible cognitive impairment. Today, only symptomatic drugs are available and therapeutic treatments, possibly acting at a...
3.
Domise M, Sauve F, Didier S, Caillerez R, Begard S, Carrier S, et al.
Cell Death Dis
. 2019 Mar;
10(3):221.
PMID: 30833547
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by synaptic loss that leads to the development of cognitive deficits. Synapses are neuronal structures that play a crucial role in memory...
4.
Evrard C, Kienlen-Campard P, Coevoet M, Opsomer R, Tasiaux B, Melnyk P, et al.
Front Cell Neurosci
. 2018 Dec;
12:435.
PMID: 30524243
Aβ peptides, the major components of Alzheimer's disease (AD) amyloid deposits, are released following sequential cleavages by secretases of its precursor named the amyloid precursor protein (APP). In addition to...
5.
Didier S, Sauve F, Domise M, Buee L, Marinangeli C, Vingtdeux V
Int J Mol Sci
. 2018 Nov;
19(12).
PMID: 30467274
Long-term memory formation depends on the expression of immediate early genes (IEGs). Their expression, which is induced by synaptic activation, is mainly regulated by the 3',5'-cyclic AMP (cAMP)-dependent protein kinase/cAMP...
6.
Marinangeli C, Didier S, Ahmed T, Caillerez R, Domise M, Laloux C, et al.
iScience
. 2018 Oct;
9:1-13.
PMID: 30368077
Although the brain accounts for only 2% of the total body mass, it consumes the most energy. Neuronal metabolism is tightly controlled, but it remains poorly understood how neurons meet...
7.
Gay M, Evrard C, Descamps F, Carato P, Renault N, Coevoet M, et al.
Eur J Med Chem
. 2018 Oct;
159:104-125.
PMID: 30268822
Dysregulation of the Amyloid Precursor Protein (APP) processing leading to toxic species of amyloid β peptides (Aβ) is central to Alzheimer's disease (AD) etiology. Aβ peptides are produced by sequential...
8.
Marinangeli C, Kluza J, Marchetti P, Buee L, Vingtdeux V
Methods Mol Biol
. 2018 Feb;
1732:289-305.
PMID: 29480483
AMP-activated protein kinase (AMPK) is the intracellular master energy sensor and metabolic regulator. AMPK is involved in cell energy homeostasis through the regulation of glycolytic flux and mitochondrial biogenesis. Interestingly,...
9.
Vingtdeux V, Zhao H, Chandakkar P, Acker C, Davies P, Marambaud P
Mol Med
. 2016 Dec;
22:841-849.
PMID: 27900387
Strategies aimed at reducing cerebral accumulation of the amyloid-β (Aβ) peptides have therapeutic potential in Alzheimer's disease (AD). Aβ immunization has proven to be effective at promoting Aβ clearance in...
10.
Domise M, Vingtdeux V
Exp Suppl
. 2016 Nov;
107:153-177.
PMID: 27812980
Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis are neurodegenerative disorders that are characterized by a progressive degeneration of nerve cells eventually leading to dementia. While these diseases...