Valerie Schumacher
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Explore the profile of Valerie Schumacher including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
1031
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Recent Articles
1.
Schulz B, Schumacher V, Ngezahayo A, Maier-Begandt D, Schadzek N, Wilhelm J, et al.
BMC Cancer
. 2023 Mar;
23(1):232.
PMID: 36899312
Background: Germ cell tumors are relatively common in young men. They derive from a non-invasive precursor, called germ cell neoplasia in situ, but the exact pathogenesis is still unknown. Thus,...
2.
Taglienti M, Graf D, Schumacher V, Kreidberg J
Development
. 2022 Jul;
149(14).
PMID: 35877077
The mammalian kidney is composed of thousands of nephrons that are formed through reiterative induction of a mesenchymal-to-epithelial transformation by a population of nephron progenitor cells. The number of nephrons...
3.
Fink C, Baal N, Wilhelm J, Sarode P, Weigel R, Schumacher V, et al.
Neoplasia
. 2021 Jun;
23(7):731-742.
PMID: 34153645
Germ cell neoplasia in situ (GCNIS) is the noninvasive precursor of testicular germ cell tumors type II, the most common cancer in young men, which originates from embryonic germ cells...
4.
Ettou S, Jung Y, Miyoshi T, Jain D, Hiratsuka K, Schumacher V, et al.
Sci Adv
. 2020 Aug;
6(30):eabb5460.
PMID: 32754639
In the context of human disease, the mechanisms whereby transcription factors reprogram gene expression in reparative responses to injury are not well understood. We have studied the mechanisms of transcriptional...
5.
Jostes S, Nettersheim D, Fellermeyer M, Schneider S, Hafezi F, Honecker F, et al.
J Cell Mol Med
. 2016 Dec;
21(7):1300-1314.
PMID: 28026145
Type II testicular germ cell cancers (TGCT) are the most frequently diagnosed tumours in young men (20-40 years) and are classified as seminoma or non-seminoma. TGCTs are commonly treated by...
6.
Nettersheim D, Jostes S, Fabry M, Honecker F, Schumacher V, Kirfel J, et al.
Oncotarget
. 2016 Aug;
7(46):74931-74946.
PMID: 27572311
In Western countries, the incidence of testicular germ cell cancers (GCC) is steadily rising over the last decades. Mostly, men between 20 and 40 years of age are affected. In...
7.
De Spiegelaere W, Dern-Wieloch J, Weigel R, Schumacher V, Schorle H, Nettersheim D, et al.
PLoS One
. 2015 Apr;
10(3):e0122515.
PMID: 25825906
Background: An appropriate normalization strategy is crucial for data analysis from real time reverse transcription polymerase chain reactions (RT-qPCR). It is widely supported to identify and validate stable reference genes,...
8.
Fiorina P, Vergani A, Bassi R, Niewczas M, Altintas M, Pezzolesi M, et al.
J Am Soc Nephrol
. 2014 Mar;
25(7):1415-29.
PMID: 24676639
Podocyte injury and resulting albuminuria are hallmarks of diabetic nephropathy, but targeted therapies to halt or prevent these complications are currently not available. Here, we show that the immune-related molecule...
9.
White S, Ohnesorg T, Notini A, Roeszler K, Hewitt J, Daggag H, et al.
PLoS One
. 2011 Mar;
6(3):e17793.
PMID: 21408189
Disorders of sex development (DSD), ranging in severity from mild genital abnormalities to complete sex reversal, represent a major concern for patients and their families. DSD are often due to...
10.
Langsdorf A, Schumacher V, Shi X, Tran T, Zaia J, Jain S, et al.
Glycobiology
. 2010 Sep;
21(2):152-61.
PMID: 20855470
Glial cell line-derived neurotrophic factor (GDNF) is a heparan sulfate (HS)-binding factor. GDNF is produced by somatic Sertoli cells, where it signals to maintain spermatogonial stem cells (SSCs) and reproduction....