Valerie F Crepin
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Explore the profile of Valerie F Crepin including associated specialties, affiliations and a list of published articles.
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47
Citations
1666
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Recent Articles
1.
McDowell M, Byrne A, Mylona E, Johnson R, Sagfors A, Crepin V, et al.
Life Sci Alliance
. 2019 May;
2(3).
PMID: 31142637
(e.g., serovars Typhi and Typhimurium) relies on translocation of effectors via type III secretion systems (T3SS). Specialization of typhoidal serovars is thought to be mediated via pseudogenesis. Here, we show...
2.
Connolly J, Slater S, OBoyle N, Goldstone R, Crepin V, Ruano-Gallego D, et al.
Nat Commun
. 2018 Dec;
9(1):5148.
PMID: 30498235
The original version of this Article contained an error in the spelling of the author David Ruano-Gallego, which was incorrectly given as David R. Gallego. This has now been corrected...
3.
Berger C, Crepin V, Roumeliotis T, Wright J, Serafini N, Pevsner-Fischer M, et al.
PLoS Pathog
. 2018 Oct;
14(10):e1007406.
PMID: 30365535
Infection with Citrobacter rodentium triggers robust tissue damage repair responses, manifested by secretion of IL-22, in the absence of which mice succumbed to the infection. Of the main hallmarks of...
4.
Connolly J, Slater S, OBoyle N, Goldstone R, Crepin V, Ruano-Gallego D, et al.
Nat Commun
. 2018 Oct;
9(1):4187.
PMID: 30305622
Niche-adaptation of a bacterial pathogen hinges on the ability to recognize the complexity of signals from the environment and integrate that information with the regulation of genes critical for infection....
5.
Mullineaux-Sanders C, Collins J, Ruano-Gallego D, Levy M, Pevsner-Fischer M, Glegola-Madejska I, et al.
Cell Rep
. 2017 Dec;
21(12):3381-3389.
PMID: 29262319
We investigated the role of commensals at the peak of infection with the colonic mouse pathogen Citrobacter rodentium. Bioluminescent and kanamycin (Kan)-resistant C. rodentium persisted avirulently in the cecal lumen...
6.
Portaliou A, Tsolis K, Loos M, Balabanidou V, Rayo J, Tsirigotaki A, et al.
EMBO J
. 2017 Nov;
36(23):3517-3531.
PMID: 29109154
Type III secretion (T3S), a protein export pathway common to Gram-negative pathogens, comprises a trans-envelope syringe, the injectisome, with a cytoplasm-facing translocase channel. Exported substrates are chaperone-delivered to the translocase,...
7.
Berger C, Crepin V, Roumeliotis T, Wright J, Carson D, Pevsner-Fischer M, et al.
Cell Metab
. 2017 Oct;
26(5):738-752.e6.
PMID: 28988824
The intestinal epithelial cells (IECs) that line the gut form a robust line of defense against ingested pathogens. We investigated the impact of infection with the enteric pathogen Citrobacter rodentium...
8.
Sandu P, Crepin V, Drechsler H, McAinsh A, Frankel G, Berger C
Infect Immun
. 2017 Jun;
85(9).
PMID: 28630074
Enterohemorrhagic (EHEC) is a diarrheagenic pathogen that colonizes the gut mucosa and induces attaching-and-effacing lesions. EHEC employs a type III secretion system (T3SS) to translocate 50 effector proteins that hijack...
9.
Pearson J, Giogha C, Muhlen S, Nachbur U, Pham C, Zhang Y, et al.
Nat Microbiol
. 2017 Feb;
2:17024.
PMID: 28191895
No abstract available.
10.
Pearson J, Giogha C, Muhlen S, Nachbur U, Pham C, Zhang Y, et al.
Nat Microbiol
. 2017 Jan;
2:16258.
PMID: 28085133
Cell death signalling pathways contribute to tissue homeostasis and provide innate protection from infection. Adaptor proteins such as receptor-interacting serine/threonine-protein kinase 1 (RIPK1), receptor-interacting serine/threonine-protein kinase 3 (RIPK3), TIR-domain-containing adapter-inducing...