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Valerie Cortin

Explore the profile of Valerie Cortin including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Pineault N, Robert A, Cortin V, Boyer L
Methods Mol Biol . 2012 Nov; 946:205-24. PMID: 23179834
Megakaryocytes (MK) are hematopoietic cells present in the bone marrow that are responsible for the production and release of platelets in the circulation. Given their very low frequency (<1%), human...
2.
Robert A, Cortin V, Garnier A, Pineault N
Methods Mol Biol . 2011 Dec; 788:219-47. PMID: 22130711
The cloning of thrombopoietin together with advances in the culture of hematopoietic stem cells have paved the way for the study of megakaryopoiesis, ongoing clinical trials and, in the future,...
3.
Pineault N, Cortin V, Boyer L, Garnier A, Robert A, Therien C, et al.
Cytotherapy . 2010 Nov; 13(4):467-80. PMID: 21090916
Background Aims: Expansion of hematopoietic progenitors ex vivo is currently investigated as a means of reducing cytopenia following stem cell transplantation. The principal objective of this study was to develop...
4.
Cortin V, Pineault N, Garnier A
Methods Mol Biol . 2008 Dec; 482:109-26. PMID: 19089352
The identification and cloning of thrombopoietin was certainly a defining moment for the study of megakaryopoiesis and thrombopoiesis ex vivo. This and other progresses made in the development of culture...
5.
Cortin V, Garnier A, Pineault N, Lemieux R, Boyer L, Proulx C
Exp Hematol . 2005 Oct; 33(10):1182-91. PMID: 16219540
Objective: A multi-step statistical strategy was applied to quantify individual and interactive effects of cytokines on megakaryopoiesis and to determine the concentration of the selected cytokines that optimize ex vivo...
6.
Cortin V, Thibault J, Jacob D, Garnier A
Biotechnol Prog . 2004 Jun; 20(3):858-63. PMID: 15176892
Human 293S cells culture for recombinant adenovirus production is traditionally carried out in batch at a maximum of 6 x 10(5) cells/mL. A previous report demonstrated that fed-batch, applied to...