Danielle Jacob
Overview
Explore the profile of Danielle Jacob including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
172
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0
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Recent Articles
1.
Shen C, Jacob D, Zhu T, Bernier A, Shao Z, Yu X, et al.
Vaccine
. 2016 May;
34(29):3381-7.
PMID: 27154390
Tuberculosis (TB) is the second leading cause of death by infectious disease worldwide. The only available TB vaccine is the Bacille Calmette-Guerin (BCG). However, parenterally administered Mycobacterium bovis BCG vaccine...
2.
Shen C, Lanthier S, Jacob D, Montes J, Beath A, Beresford A, et al.
Vaccine
. 2011 Nov;
30(2):300-6.
PMID: 22079076
Rabies virus is an important causative agent of disease resulting in an acute infection of the nervous system and death. Although curable if treated in a timely manner, rabies remains...
3.
Petiot E, Jacob D, Lanthier S, Lohr V, Ansorge S, Kamen A
BMC Biotechnol
. 2011 Sep;
11:84.
PMID: 21884612
Background: Cell culture-based production of influenza vaccine remains an attractive alternative to egg-based production. Short response time and high production yields are the key success factors for the broader adoption...
4.
Le Ru A, Jacob D, Transfiguracion J, Ansorge S, Henry O, Kamen A
Vaccine
. 2010 Mar;
28(21):3661-71.
PMID: 20347632
Cell culture processes offer an attractive alternative to conventional chicken egg-based influenza vaccine production methods. However, most protocols still rely on the use of adherent cells, which makes process scale-up...
5.
Development of a simple and high-yielding fed-batch process for the production of influenza vaccines
Meghrous J, Mahmoud W, Jacob D, Chubet R, Cox M, Kamen A
Vaccine
. 2009 Nov;
28(2):309-16.
PMID: 19879996
A robust and reliable GMP-compatible fed-batch process was successfully developed for the production of recombinant hemagglutinin (rHA) proteins by expresSF cells. The feeding solution, feeding strategy as well as the...
6.
Meneses-Acosta A, Dormond E, Jacob D, Tom R, Bernier A, Perret S, et al.
J Virol Methods
. 2007 Dec;
148(1-2):106-14.
PMID: 18079009
Helper-dependent adenovirus (HDAd), deleted in all viral protein-coding sequences has been designed to reduce immune response and favor long-term expression of therapeutic genes in clinical programs. Its production requires co-infection...
7.
Aucoin M, Jacob D, Chahal P, Meghrous J, Bernier A, Kamen A
Methods Mol Biol
. 2007 Oct;
388:281-96.
PMID: 17951776
The ability to make a large variety of virus-like particles (VLPs) has been successfully achieved in the baculovirus expression vector system (BEVS)/insect cell system. The production and scale-up of these...
8.
Durocher Y, Pham P, St-Laurent G, Jacob D, Cass B, Chahal P, et al.
J Virol Methods
. 2007 May;
144(1-2):32-40.
PMID: 17467815
Recombinant adeno-associated virus (rAAV) has emerged in recent years as a promising gene therapy vector that may be used in the treatment of diverse human diseases. The major obstacle to...
9.
Transfiguracion J, Jorio H, Meghrous J, Jacob D, Kamen A
J Virol Methods
. 2007 Feb;
142(1-2):21-8.
PMID: 17306891
Recombinant baculoviruses carrying mammalian expression cassettes or "BacMam" are promising gene delivery vehicles shown to transduce mammalian cells efficiently both in vitro and in vivo. These viruses are vectors of...
10.
Meghrous J, Aucoin M, Jacob D, Chahal P, Arcand N, Kamen A
Biotechnol Prog
. 2005 May;
21(1):154-60.
PMID: 15903253
Production of recombinant adeno-associated viral vectors using a baculovirus/insect cell system at various scales is presented. Shake flask studies were conducted to assess conditions to be used in bioreactors. Two...