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Valeria A Risso

Explore the profile of Valeria A Risso including associated specialties, affiliations and a list of published articles. Areas
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Articles 39
Citations 613
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Recent Articles
1.
Keser M, Mateljak I, Kittl R, Ludwig R, Risso V, Sanchez-Ruiz J, et al.
ACS Synth Biol . 2024 Dec; 14(1):239-246. PMID: 39670334
Galactose oxidase (GOase) is a versatile biocatalyst with a wide range of potential applications, ranging from synthetic chemistry to bioelectrochemical devices. Previous GOase engineering by directed evolution generated the M-RQW...
2.
Gutierrez-Rus L, Gamiz-Arco G, Gavira J, Gaucher E, Risso V, Sanchez-Ruiz J
Mol Biol Evol . 2023 May; 40(6). PMID: 37235753
Enzymes catalyze the chemical reactions of life. For nearly half of known enzymes, catalysis requires the binding of small molecules known as cofactors. Polypeptide-cofactor complexes likely formed at a primordial...
3.
Gutierrez-Rus L, Gamiz-Arco G, Gavira J, Gaucher E, Risso V, Sanchez-Ruiz J
bioRxiv . 2023 Mar; PMID: 36993774
Enzymes catalyze the chemical reactions of life. For nearly half of known enzymes, catalysis requires the binding of small molecules known as cofactors. Polypeptide-cofactor complexes likely formed at a primordial...
4.
Severino R, Moreno-Paz M, Puente-Sanchez F, Sanchez-Garcia L, Risso V, Sanchez-Ruiz J, et al.
Anal Chem . 2023 Mar; 95(12):5323-5330. PMID: 36926836
Several mass spectrometry and spectroscopic techniques have been used in the search for molecular biomarkers on Mars. A major constraint is their capability to detect and identify large and complex...
5.
Gutierrez-Rus L, Alcalde M, Risso V, Sanchez-Ruiz J
Int J Mol Sci . 2022 Aug; 23(16). PMID: 36012203
The routine generation of enzymes with completely new active sites is a major unsolved problem in protein engineering. Advances in this field have thus far been modest, perhaps due, at...
6.
Glavina J, Rodriguez de la Vega R, Risso V, Leonetti C, Chemes L, Sanchez I
J Mol Biol . 2022 Mar; 434(10):167563. PMID: 35351519
Over one hundred Mastadenovirus types infect seven orders of mammals. Virus-host coevolution may involve cospeciation, duplication, host switch and partial extinction events. We reconstruct Mastadenovirus diversification, finding that while cospeciation...
7.
Gamiz-Arco G, Risso V, Gaucher E, Gavira J, Naganathan A, Ibarra-Molero B, et al.
J Mol Biol . 2021 Oct; 433(24):167321. PMID: 34687715
Obligate symbionts typically exhibit high evolutionary rates. Consequently, their proteins may differ considerably from their modern and ancestral homologs in terms of both sequence and properties, thus providing excellent models...
8.
Luzon-Hidalgo R, Risso V, Delgado A, Ibarra-Molero B, Sanchez-Ruiz J
STAR Protoc . 2021 Sep; 2(3):100784. PMID: 34485945
A general protocol for the experimental assessment of bacteriophage adaptation to new hosts is described. We use as a model system the lytic phage T7 and an strain modified to...
9.
Luzon-Hidalgo R, Risso V, Delgado A, Andres-Leon E, Ibarra-Molero B, Sanchez-Ruiz J
iScience . 2021 Apr; 24(4):102257. PMID: 33817569
Viruses interact extensively with the host molecular machinery, but the underlying mechanisms are poorly understood. Bacteriophage T7 recruits the small protein thioredoxin of the host as an essential processivity factor...
10.
Modi T, Risso V, Martinez-Rodriguez S, Gavira J, Mebrat M, Van Horn W, et al.
Nat Commun . 2021 Mar; 12(1):1852. PMID: 33767175
TEM-1 β-lactamase degrades β-lactam antibiotics with a strong preference for penicillins. Sequence reconstruction studies indicate that it evolved from ancestral enzymes that degraded a variety of β-lactam antibiotics with moderate...