Valentina DellOste
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Explore the profile of Valentina DellOste including associated specialties, affiliations and a list of published articles.
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Citations
883
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Recent Articles
11.
Novel antiviral activity of PAD inhibitors against human beta-coronaviruses HCoV-OC43 and SARS-CoV-2
Pasquero S, Gugliesi F, Griffante G, DellOste V, Biolatti M, Albano C, et al.
Antiviral Res
. 2022 Mar;
200:105278.
PMID: 35288208
The current SARS-CoV-2 pandemic, along with the likelihood that new coronavirus strains will appear in the nearby future, highlights the urgent need to develop new effective antiviral agents. In this...
12.
Toscani A, Denaro R, Castillo Pacheco S, Biolatti M, Anselmi S, DellOste V, et al.
Molecules
. 2021 Aug;
26(16).
PMID: 34443515
Current therapy against herpes simplex viruses (HSV) relies on the use of a few nucleoside antivirals such as acyclovir, famciclovir and valacyclovir. However, the current drugs are ineffective against latent...
13.
DellOste V, Spyrakis F, Prandi C
Molecules
. 2021 Aug;
26(15).
PMID: 34361731
Strigolactones (SLs) are a class of sesquiterpenoid plant hormones that play a role in the response of plants to various biotic and abiotic stresses. When released into the rhizosphere, they...
14.
Griffante G, Gugliesi F, Pasquero S, DellOste V, Biolatti M, Salinger A, et al.
Nat Commun
. 2021 Jun;
12(1):3910.
PMID: 34162877
Citrullination is the conversion of arginine-to-citrulline by protein arginine deiminases (PADs), whose dysregulation is implicated in the pathogenesis of various types of cancers and autoimmune diseases. Consistent with the ability...
15.
Galitska G, Coscia A, Forni D, Steinbrueck L, Meo S, Biolatti M, et al.
Front Immunol
. 2021 Apr;
12:532484.
PMID: 33897679
Human cytomegalovirus (HCMV) infection often leads to systemic disease in immunodeficient patients and congenitally infected children. Despite its clinical significance, the exact mechanisms contributing to HCMV pathogenesis and clinical outcomes...
16.
Riva G, Albano C, Gugliesi F, Pasquero S, Castillo Pacheco S, Pecorari G, et al.
Int J Mol Sci
. 2021 Feb;
22(3).
PMID: 33573337
Besides smoking and alcohol, human papillomavirus (HPV) is a factor promoting head and neck squamous cell carcinoma (HNSCC). In some human tumors, including HNSCC, a number of mutations are caused...
17.
Gugliesi F, Pasquero S, Griffante G, Scutera S, Albano C, Castillo Pacheco S, et al.
Viruses
. 2021 Feb;
13(2).
PMID: 33567734
Human cytomegalovirus (HCMV) is a ubiquitous double-stranded DNA virus belonging to the β-subgroup of the herpesvirus family. After the initial infection, the virus establishes latency in poorly differentiated myeloid precursors...
18.
Meo S, DellOste V, Molfetta R, Tassinari V, Lotti L, Vespa S, et al.
PLoS Pathog
. 2020 Sep;
16(9):e1008855.
PMID: 32986788
SAMHD1 is a host restriction factor that functions to restrict both retroviruses and DNA viruses, based on its nuclear deoxynucleotide triphosphate (dNTP) hydrolase activity that limits availability of intracellular dNTP...
19.
Biolatti M, Blangetti M, DArrigo G, Spyrakis F, Cappello P, Albano C, et al.
Microorganisms
. 2020 May;
8(5).
PMID: 32397638
The human cytomegalovirus (HCMV) is a widespread pathogen and is associated with severe diseases in immunocompromised individuals. Moreover, HCMV infection is the most frequent cause of congenital malformation in developed...
20.
Mozzi A, Biolatti M, Cagliani R, Forni D, DellOste V, Pontremoli C, et al.
PLoS Pathog
. 2020 May;
16(5):e1008476.
PMID: 32384127
Cytomegaloviruses (order Herpesvirales) display remarkable species-specificity as a result of long-term co-evolution with their mammalian hosts. Human cytomegalovirus (HCMV) is exquisitely adapted to our species and displays high genetic diversity....