Vadim Markovtsov
Overview
Explore the profile of Vadim Markovtsov including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
506
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0
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Recent Articles
11.
Jenkins Y, Sun T, Markovtsov V, Foretz M, Li W, Nguyen H, et al.
PLoS One
. 2013 Dec;
8(12):e81870.
PMID: 24339975
Modulation of mitochondrial function through inhibiting respiratory complex I activates a key sensor of cellular energy status, the 5'-AMP-activated protein kinase (AMPK). Activation of AMPK results in the mobilization of...
12.
Shide K, Kameda T, Markovtsov V, Shimoda H, Tonkin E, Fang S, et al.
Blood
. 2011 May;
117(25):6866-75.
PMID: 21531978
The activating mutations in JAK2 (including JAK2V617F) that have been described in patients with myeloproliferative neoplasms (MPNs) are linked directly to MPN pathogenesis. We developed R723, an orally bioavailable small...
13.
Hitoshi Y, Lin N, Payan D, Markovtsov V
Int J Hematol
. 2010 Mar;
91(2):189-200.
PMID: 20191331
Janus kinases (JAKs) are critical components of cytokine signaling pathways which regulate immunity, inflammation, hematopoiesis, growth, and development. The recent discovery of JAK2-activating mutations as a causal event in the...
14.
Mclaughlin J, Markovtsov V, Li H, Wong S, Gelman M, Zhu Y, et al.
J Cancer Res Clin Oncol
. 2009 Jul;
136(1):99-113.
PMID: 19609559
Purpose: Aurora kinases play a key role in mitotic progression. Over-expression of Aurora kinases is found in several human cancers and correlated with histological malignancy and clinical outcomes. Therefore, Aurora...
15.
Jenkins Y, Markovtsov V, Lang W, Sharma P, Pearsall D, Warner J, et al.
Mol Biol Cell
. 2005 Oct;
16(12):5621-9.
PMID: 16195352
Early cellular events associated with tumorigenesis often include loss of cell cycle checkpoints or alteration in growth signaling pathways. Identification of novel genes involved in cellular proliferation may lead to...
16.
Amir-Ahmady B, Boutz P, Markovtsov V, Phillips M, Black D
RNA
. 2005 Apr;
11(5):699-716.
PMID: 15840818
Polypyrimidine tract binding protein (PTB) is known to silence the splicing of many alternative exons. However, exons repressed by PTB are affected by other RNA regulatory elements and proteins. This...
17.
Mustaev A, Zaychikov E, Grachev M, Kozlov M, Severinov K, Epshtein V, et al.
Methods Enzymol
. 2004 Jan;
371:191-206.
PMID: 14712701
No abstract available.
18.
Rooke N, Markovtsov V, Cagavi E, Black D
Mol Cell Biol
. 2003 Mar;
23(6):1874-84.
PMID: 12612063
The splicing of the c-src exon N1 is controlled by an intricate combination of positive and negative RNA elements. Most previous work on these sequences focused on intronic elements found...
19.
Epshtein V, Mustaev A, Markovtsov V, Bereshchenko O, Nikiforov V, Goldfarb A
Mol Cell
. 2002 Nov;
10(3):623-34.
PMID: 12408829
Each elementary step of transcription involves translocation of the 3' terminus of RNA in the RNA polymerase active center, followed by the entry of a nucleoside triphosphate. The structural basis...