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V Summa

Explore the profile of V Summa including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 187
Followers 0
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Recent Articles
1.
Baggio B, Giannossi M, Medici L, Summa V, Tateo F
J Xray Sci Technol . 2013 Jan; 20(4):489-98. PMID: 23324789
The qualitative and quantitative analyses of crystalluria have clinical significance in the diagnosis and prognosis of urolithiasis. The aim of this paper is to provide a new accurate methodology to...
2.
Tshilolo L, Summa V, Gregorj C, Kinsiama C, Bazeboso J, Avvisati G, et al.
Anemia . 2012 Jul; 2012:105349. PMID: 22830000
High HbF levels and F cells are correlated with reduced morbidity and mortality in sickle cell disease (SCD). This paper was designed to determine the HbF and F cells levels...
3.
Chiarella P, Summa V, De Santis S, Signori E, Picardi E, Pesole G, et al.
Curr Mol Med . 2012 Feb; 12(5):547-65. PMID: 22300134
Philadelphia (Ph+) positive leukaemias are an example of haematological malignant diseases where different chromosomal rearrangements involving both BCR and ABL1 genes generate a variety of chimeric proteins (BCR/ABL1 p210, p190...
4.
Tshilolo L, Wembonyama S, Summa V, Avvisati G
Med Trop (Mars) . 2011 Apr; 70(5-6):459-63. PMID: 21520647
Introduction: Sickle cell disease is associated with a wide range of clinical and laboratory findings depending on genetic modulators and environmental factors. The most severe forms of sickle cell disease...
5.
Monteagudo E, Fonsi M, Chu X, Bleasby K, Evers R, Pucci V, et al.
Xenobiotica . 2010 Oct; 40(12):826-39. PMID: 20925584
Compound A ((1aR,5S,8S,10R,22aR)-5-tert-butyl-N-{(1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethenylcyclopropyl}-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadecino[12,11-b]quinoline-8-carboxamide) is a prototype of a series of subnanomolar inhibitors of genotypes 1, 2, and 3 hepatitis C virus (HCV) NS3/4A proteases. HCV NS3/4A protease inhibitors have demonstrated...
6.
Monteagudo E, Pesci S, Taliani M, Fiore F, Petrocchi A, Nizi E, et al.
Xenobiotica . 2007 Sep; 37(9):1000-12. PMID: 17896326
(19)F-nuclear magnetic resonance (NMR) has been extensively used in a drug-discovery programme to support the selection of candidates for further development. Data on an early lead compound, N-(4-fluorobenzyl)-5-hydroxy-1-methyl-2-(4-methylmorpholin-3-yl)-6-oxo-1,6-dihydropyrimidine-4-carboxamide (compound A...
7.
Summa V, Mordasini D, Roger F, Bens M, Martin P, Vandewalle A, et al.
J Biol Chem . 2001 Oct; 276(50):47087-93. PMID: 11598118
Aldosterone controls extracellular volume and blood pressure by regulating Na+ reabsorption, in particular by epithelia of the distal nephron. A main regulatory site of this transcellular transport is the epithelial...
8.
Loffing J, Summa V, Zecevic M, Verrey F
Curr Opin Nephrol Hypertens . 2001 Aug; 10(5):667-75. PMID: 11496063
The aldosterone-sensitive distal nephron extends from the second part of the distal convoluted tubule to the inner medullary collecting duct. As recently shown, aldosterone increases within two hours the abundance...
9.
Verrey F, Pearce D, Pfeiffer R, Spindler B, Mastroberardino L, Summa V, et al.
Kidney Int . 2000 Apr; 57(4):1277-82. PMID: 10760054
The aldosterone-induced increase in sodium reabsorption across tight epithelia can be divided schematically into two functional phases: an early regulatory phase starting after a lag period of 20 to 60...
10.
Rossier G, Meier C, Bauch C, Summa V, Sordat B, Verrey F, et al.
J Biol Chem . 1999 Nov; 274(49):34948-54. PMID: 10574970
Glycoprotein-associated amino acid transporters (gpaAT) are permease-related proteins that require heterodimerization to express their function. So far, four vertebrate gpaATs have been shown to associate with 4F2hc/CD98 for functional expression,...