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V S Shankar

Explore the profile of V S Shankar including associated specialties, affiliations and a list of published articles. Areas
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Articles 32
Citations 195
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Recent Articles
1.
Wimalawansa S, Shankar V, Simmins D, Wimalawansa S
J Musculoskelet Neuronal Interact . 2005 Mar; 1(2):141-3. PMID: 15758508
Treatment with cyclosporin A (CsA) following solid organ transplantations such as heart or liver generally results in bone loss. However, in vitro studies show that CsA inhibits bone resorption. Our...
2.
Shankar V, Simon B, Bax C, Pazianas M, Moonga B, Adebanjo O, et al.
J Cell Physiol . 1998 Aug; 176(3):537-44. PMID: 9699506
We report the effects of pulsed electromagnetic fields (PEMFs) on the responsiveness of osteoclasts to cellular, hormonal, and ionic signals. Osteoclasts isolated from neonatal rat long bones were dispersed onto...
3.
Zaidi M, Shankar V, Adebanjo O, Lai F, Pazianas M, Sunavala G, et al.
Am J Physiol . 1996 Sep; 271(3 Pt 2):F637-44. PMID: 8853426
Certain eukaryotic cells can sense changes in their extracellular Ca2+ concentration through molecular structures termed Ca(2+)-sensing receptors (CaRs). We have shown recently that in the bone-resorbing osteoclast, a unique cell...
4.
Ganjoo A, Johnson W, Gordon R, Jain D, Lang G, Shankar V
J Thorac Cardiovasc Surg . 1996 Aug; 112(2):551-3. PMID: 8751532
No abstract available.
5.
Adebanjo O, Shankar V, Pazianas M, Simon B, Lai F, Huang C, et al.
Am J Physiol . 1996 Mar; 270(3 Pt 2):F469-75. PMID: 8780250
We demonstrated recently that the divalent cation-sensing receptor on the osteoclast, the Ca2+ receptor (CaR), is a functional component of a cell surface-expressed ryanodine receptor-like molecule (RyR). The objective of...
6.
Zaidi M, Shankar V, Tunwell R, Adebanjo O, Mackrill J, Pazianas M, et al.
J Clin Invest . 1995 Sep; 96(3):1582-90. PMID: 7657829
Ryanodine receptors (RyRs) reside in microsomal membranes where they gate Ca2+ release in response to changes in the cytosolic Ca2+ concentration. In the osteoclast, a divalent cation sensor, the Ca2+...
7.
Pazianas M, Adebanjo O, Shankar V, James S, Colston K, Maxwell J, et al.
Biochem Biophys Res Commun . 1995 May; 210(3):948-53. PMID: 7763267
We report that the divalent cation Ni2+ elicits elevations in the cytosolic free Ca2+ concentration ([Ca2+]) in cultured enterocytes. These elevations were monophasic, each response consisting of a rapid initial...
8.
Shankar V, Pazianas M, Huang C, Simon B, Adebanjo O, Zaidi M
Am J Physiol . 1995 Mar; 268(3 Pt 2):F447-54. PMID: 7900844
A ryanodine-sensitive pathway is involved in intracellular Ca2+ release in response to activation of the osteoclast cell surface Ca2+ receptor. We now report that the ryanodine-receptor modulator, caffeine itself released...
9.
Shankar V, Huang C, Adebanjo O, Simon B, Alam A, Moonga B, et al.
J Cell Physiol . 1995 Jan; 162(1):1-8. PMID: 7814441
Osteoclasts are known to possess a divalent cation-sensitive receptor, the Ca2+ receptor (CaR). The latter monitors changes in the local Ca2+ concentration generated as a result of hydroxyapatite dissolution. CaR...
10.
Adebanjo O, Pazianas M, Zaidi A, Shankar V, Bascal Z, Dacke C, et al.
J Endocrinol . 1994 Nov; 143(2):375-81. PMID: 7830000
Prostaglandins exert marked but transient inhibitory effects on bone resorption. The present study examines the effects of prostacyclin (0.15 to 25 microM) on the morphology of freshly disaggregated rat osteoclasts....