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V Pozsgay

Explore the profile of V Pozsgay including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 28
Citations 189
Followers 0
Related Specialties
Biochemistry
Endocrinology
Chemistry
Top 10 Co-Authors
J B Robbins
H J Jennings
B Coxon
R Schneerson
A Liptak
C P Glaudemans
D L Kasper
G Batta
L PANNELL
P Kovac
Published In
Carbohydr Res
J Antibiot (Tokyo)
J Biol Chem
Infect Immun
Glycoconj J
Affiliations
Soon will be listed here.
Recent Articles
1.
Oligosaccharide-protein conjugates as vaccine candidates against bacteria
Pozsgay V
Adv Carbohydr Chem Biochem . 2000 Oct; 56:153-99. PMID: 11039111
No abstract available.
2.
A new, lipophilic p-alkoxybenzyl ether protecting group and its use in the synthesis of a disaccharide
Pozsgay V
Org Lett . 2000 May; 1(3):477-9. PMID: 10822587
[formula: see text] In contrast to major advances in the chemical synthesis of oligosaccharides, the methods of purification of the intermediates are essentially the same as they were decades ago....
3.
NMR spectroscopy, molecular dynamics, and conformation of a synthetic octasaccharide fragment of the O-specific polysaccharide of Shigella dysenteriae type 1
Coxon B, Sari N, Batta G, Pozsgay V
Carbohydr Res . 2000 Mar; 324(1):53-65. PMID: 10723612
A synthetic octasaccharide fragment (2) of the O-specific polysaccharide (1) of Shigella dysenteriae type 1 has been studied as its methyl glycoside by one- and two-dimensional homo- and heteronuclear NMR...
4.
Synthesis of the repeating unit of the O-specific polysaccharide of Shigella sonnei and quantitation of its serologic activity
Toth A, MEDGYES A, Bajza I, Liptak A, Batta G, KONTROHR T, et al.
Bioorg Med Chem Lett . 2000 Jan; 10(1):19-21. PMID: 10636234
The chemical synthesis of the zwitterionic disaccharide 2 is described that corresponds to the repeating unit of the O-specific polysaccharide (1) of the gram-negative human pathogen Shigella sonnei. Passive hemolysis...
5.
Synthesis of L-glucose from D-gulono-1,4-lactone
Hajko J, Liptak A, Pozsgay V
Carbohydr Res . 1999 Dec; 321(1-2):116-20. PMID: 10612005
An efficient method for the synthesis of L-glucose from D-gulono-1,4-lactone via 1,2,3,4,5-penta-O-benzyl/acetyl/benzoyl-D-gulitol is described in 34-53% overall yield.
6.
Syntheses and immunologic properties of Escherichia coli O157 O-specific polysaccharide and Shiga toxin 1 B subunit conjugates in mice
Konadu E, Donohue-Rolfe A, Calderwood S, Pozsgay V, Shiloach J, Robbins J, et al.
Infect Immun . 1999 Oct; 67(11):6191-3. PMID: 10531288
Escherichia coli O157 is the major cause of diarrhea-associated hemolytic uremic syndrome (HUS). Strains causing HUS contain either Shiga toxin 1 (Stx1) or Stx2, or both. In adult volunteers, conjugate...
7.
Protein conjugates of synthetic saccharides elicit higher levels of serum IgG lipopolysaccharide antibodies in mice than do those of the O-specific polysaccharide from Shigella dysenteriae type 1
Pozsgay V, Chu C, PANNELL L, Wolfe J, Robbins J, Schneerson R
Proc Natl Acad Sci U S A . 1999 Apr; 96(9):5194-7. PMID: 10220442
Our development of vaccines to prevent shigellosis is based on the hypothesis that a critical (protective) level of serum IgG to the O-specific polysaccharide (O-SP) domain of Shigella lipopolysaccharide (LPS)...
8.
Measurement of interglycosidic 3JCH coupling constants of selectively 13C labeled oligosaccharides by 2D J-resolved 1H NMR spectroscopy
Pozsgay V, Sari N, Coxon B
Carbohydr Res . 1998 Jul; 308(1-2):229-38. PMID: 9675362
Tri-, tetra-, and penta-saccharide fragments of the O-specific polysaccharide of Shigella dysenteriae type 1 have been prepared in which a D-galactose residue of each oligosaccharide methyl glycoside derivative contains a...
9.
Conformational stabilization of the altruronic acid residue in the O-specific polysaccharide of Shigella sonnei/Plesiomonas shigelloides
Batta G, Liptak A, Schneerson R, Pozsgay V
Carbohydr Res . 1998 Apr; 305(1):93-9. PMID: 9534229
Complete assignments for the 1H- and the 13C-NMR spectra of the O-specific polysaccharide of S. sonnei/Plesiomonas shigelloides are reported. Evidence is presented that in this polysaccharide both pyranose residues exist...
10.
Of four murine, anti-Shigella dysenteriae type 1 O-polysaccharide antibodies, three employ V-genes that differ extensively from those of the fourth
Miller C, Karpas A, Schneerson R, Huppi K, Kovac P, Pozsgay V, et al.
Mol Immunol . 1996 Nov; 33(16):1217-22. PMID: 9129157
Three murine, monoclonal antibodies, IgM 5286 F2, IgM 5297 C1, and IgG 5338 H4 were generated against Shigella dysenteriae type 1 O-specific polysaccharide (O-SP)-conjugate. They are specific for the O-SP,...