V P Sukhatme
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Explore the profile of V P Sukhatme including associated specialties, affiliations and a list of published articles.
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132
Citations
5181
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Recent Articles
1.
Hanai J, Doro N, Seth P, Sukhatme V
Cell Death Dis
. 2013 Jun;
4:e696.
PMID: 23807225
ATP citrate lyase (ACL) knockdown (KD) causes tumor suppression and induces differentiation. We have previously reported that ACL KD reverses epithelial-mesenchymal transition (EMT) in lung cancer cells. Because EMT is...
2.
Bhatt R, Zurita A, ONeill A, Norden-Zfoni A, Zhang L, Wu H, et al.
Br J Cancer
. 2011 Jun;
105(1):112-7.
PMID: 21673679
Background: Circulating endothelial cells (CECs) are a candidate biomarker for monitoring angiogenesis in cancer. Circulating endothelial cell subsets are mobilised by angiogenic mediators. Because of the highly angiogenic phenotype of...
3.
Zacharski L, Sukhatme V
J Thromb Haemost
. 2005 Mar;
3(3):424-7.
PMID: 15748226
No abstract available.
4.
Karihaloo A, Karumanchi S, Barasch J, Jha V, Nickel C, Yang J, et al.
Proc Natl Acad Sci U S A
. 2001 Oct;
98(22):12509-14.
PMID: 11606725
Endostatin (ES) inhibits endothelial cell migration and has been found to bind to glypicans (Gpcs) on both endothelial cells and renal epithelial cells. We examined the possibility that ES might...
5.
Karumanchi S, Jha V, Ramchandran R, Karihaloo A, Tsiokas L, Chan B, et al.
Mol Cell
. 2001 May;
7(4):811-22.
PMID: 11336704
Endostatin, a collagen XVIII fragment, is a potent anti-angiogenic protein. We sought to identify its endothelial cell surface receptor(s). Alkaline phosphatase- tagged endostatin bound endothelial cells revealing two binding affinities....
6.
Jiang L, Jha V, Dhanabal M, Sukhatme V, Alper S
Am J Physiol Cell Physiol
. 2001 Apr;
280(5):C1140-50.
PMID: 11287327
Intracellular signaling mechanisms by the angiogenesis inhibitors endostatin and angiostatin remain poorly understood. We have found that endostatin (2 microg/ml) and angiostatin (5 microg/ml) elicited transient, approximately threefold increases in...
7.
Karumanchi S, Jiang L, Knebelmann B, Alper S, Sukhatme V
Physiol Genomics
. 2001 Apr;
5(3):119-28.
PMID: 11285365
Mutations in the von Hippel-Lindau (VHL) tumor suppressor gene are thought to play a critical role in the pathogenesis of both sporadic and VHL disease-associated clear-cell renal carcinomas (RCC). Differential...
8.
Hanaoka K, Qian F, Boletta A, Bhunia A, Piontek K, Tsiokas L, et al.
Nature
. 2001 Jan;
408(6815):990-4.
PMID: 11140688
The human kidney is composed of roughly 1.2-million renal tubules that must maintain their tubular structure to function properly. In autosomal dominant polycystic kidney disease (ADPKD) cysts develop from renal...
9.
Hanna N, Seetharam S, Mauceri H, Beckett M, Jaskowiak N, Salloum R, et al.
Cancer J
. 2000 Nov;
6(5):287-93.
PMID: 11079167
Purpose: The purpose of this study was to evaluate whether endostatin, an antiangiogenic cleavage fragment of collagen XVIII, enhances the antitumor effects of ionizing radiation (IR). Endostatin was injected to...
10.
Yokoyama Y, Green J, Sukhatme V, Ramakrishnan S
Cancer Res
. 2000 Sep;
60(16):4362-5.
PMID: 10969778
A transgenic mouse model was used to evaluate the effect of endostatin treatment on spontaneous tumorigenesis. In this model system, female mice develop multiple mammary adenocarcinomas and male mice develop...