V M Tesmer
Overview
Explore the profile of V M Tesmer including associated specialties, affiliations and a list of published articles.
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10
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1107
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Recent Articles
1.
Huffman K, Levene S, Tesmer V, Shay J, Wright W
J Biol Chem
. 2000 Apr;
275(26):19719-22.
PMID: 10787419
Most normal diploid human cells do not express telomerase activity and are unable to maintain telomere length with ongoing cell divisions. We show that the length of the single-stranded G-rich...
2.
Wright W, Tesmer V, Liao M, Shay J
Exp Cell Res
. 1999 Sep;
251(2):492-9.
PMID: 10471333
Telomeres in yeast are late replicating. Genes placed next to telomeres in yeast can be repressed (telomere positional effects), leading to the hypothesis that telomeres may be heterochromatic and may...
3.
Tesmer V, Ford L, Holt S, Frank B, Yi X, Aisner D, et al.
Mol Cell Biol
. 1999 Aug;
19(9):6207-16.
PMID: 10454567
We have mapped the 5' and 3' boundaries of the region of the human telomerase RNA (hTR) that is required to produce activity with the human protein catalytic subunit (hTERT)...
4.
Yi X, Tesmer V, Shay J, Wright W
Mol Cell Biol
. 1999 May;
19(6):3989-97.
PMID: 10330139
The human telomerase RNA component (hTR) is present in normal somatic cells at lower levels than in cancer-derived cell lines. To understand the mechanisms regulating hTR levels in different cell...
5.
Holt S, Aisner D, Baur J, Tesmer V, Dy M, Ouellette M, et al.
Genes Dev
. 1999 Apr;
13(7):817-26.
PMID: 10197982
Most normal human diploid cells have no detectable telomerase; however, expression of the catalytic subunit of telomerase is sufficient to induce telomerase activity and, in many cases, will bypass normal...
6.
Weinrich S, Pruzan R, Ma L, Ouellette M, Tesmer V, Holt S, et al.
Nat Genet
. 1997 Dec;
17(4):498-502.
PMID: 9398860
The maintenance of chromosome termini, or telomeres, requires the action of the enzyme telomerase, as conventional DNA polymerases cannot fully replicate the ends of linear molecules. Telomerase is expressed and...
7.
Wright W, Tesmer V, Huffman K, Levene S, Shay J
Genes Dev
. 1997 Nov;
11(21):2801-9.
PMID: 9353250
Telomeres protect the ends of linear chromosomes from degradation and abnormal recombination events, and in vertebrates may be important in cellular senescence and cancer. However, very little is known about...
8.
Tesmer V, Bina M
J Mol Biol
. 1996 Sep;
262(3):327-35.
PMID: 8844998
Previous studies have shown that in human T-cells (Jurkat) and hepatoma cells (HepG2), exogenous NF-IL6 can activate HIV-1 gene expression even in the absence of its consensus binding elements in...
9.
Tesmer V, Rajadhyaksha A, Babin J, Bina M
Proc Natl Acad Sci U S A
. 1993 Aug;
90(15):7298-302.
PMID: 8346247
An upstream control region in the long terminal repeat (LTR) of human immunodeficiency virus type 1 (HIV-1) includes a potential negative regulatory element (NRE1). Cotransfecting multimers of a sequence spanning...
10.
Chakerian A, Tesmer V, Manly S, Brackett J, Lynch M, Hoh J, et al.
J Biol Chem
. 1991 Jan;
266(3):1371-4.
PMID: 1988425
Amino acid sequence homology between the carboxyl-terminal segment of the lac repressor and eukaryotic proteins containing the leucine zipper motif with associated basic DNA binding region (bZIP) has been identified....