Uyen Phan
Overview
Explore the profile of Uyen Phan including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
108
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0
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Recent Articles
1.
Tran T, Grein J, Selman M, Annamalai L, Yearley J, Blumenschein W, et al.
Mol Ther Oncol
. 2024 May;
32(2):200807.
PMID: 38745749
V937 is an investigational, genetically unmodified Kuykendall strain of coxsackievirus A21, which has been evaluated in the clinic for advanced solid tumor malignancies. V937 specifically infects and lyses tumor cells...
2.
Sam M, Selman M, Zhao W, Jung J, Willingham A, Phan U, et al.
J Virol
. 2023 Apr;
97(5):e0030923.
PMID: 37070982
Coxsackievirus A21 (CVA21) is a naturally occurring RNA virus that, in preclinical studies and clinical trials, has demonstrated promising potential in treating a range of malignancies. Other oncolytic viruses, such...
3.
Targeted degradation of PCNA outperforms stoichiometric inhibition to result in programed cell death
Chang S, Gopal P, Lim S, Wei X, Chandramohan A, Mangadu R, et al.
Cell Chem Biol
. 2022 Nov;
29(11):1601-1615.e7.
PMID: 36318925
Biodegraders are targeted protein degradation constructs composed of mini-proteins/peptides linked to E3 ligase receptors. We gained deeper insights into their utility by studying Con1-SPOP, a biodegrader against proliferating cell nuclear...
4.
Ng S, Lim S, Sim A, Mangadu R, Lau A, Zhang C, et al.
Sci Rep
. 2022 Aug;
12(1):14087.
PMID: 35982220
Immune checkpoint blockade (ICB) leads to durable and complete tumour regression in some patients but in others gives temporary, partial or no response. Accordingly, significant efforts are underway to identify...
5.
Laudanski K, Jihane H, Antalosky B, Ghani D, Phan U, Hernandez R, et al.
Front Immunol
. 2021 Jun;
12:650465.
PMID: 34177897
Identification of novel immune biomarkers to gauge the underlying pathology and severity of COVID-19 has been difficult due to the lack of longitudinal studies. Here, we analyzed serum collected upon...
6.
Moi J, Phan U, de Gruchy A, Liew D, Yuen T, Cunningham J, et al.
BMJ Open
. 2018 Oct;
8(10):e019275.
PMID: 30309987
Objectives: To report on the design, implementation and evaluation of the safety and effectiveness of the Back pain Assessment Clinic (BAC) model. Design: BAC is a new, community-based specialist service...
7.
Harding P, Burge A, Walter K, Shaw B, Page C, Phan U, et al.
Physiotherapy
. 2017 Oct;
104(1):98-106.
PMID: 28964524
Objective: To evaluate outcomes following a state-wide implementation of post arthroplasty review (PAR) clinics for patients following total hip and knee arthroplasty, led by advanced musculoskeletal physiotherapists in collaboration with...
8.
Guadagnoli M, Kimberley F, Phan U, Cameron K, Vink P, Rodermond H, et al.
Blood
. 2011 May;
117(25):6856-65.
PMID: 21543761
APRIL (A proliferation-inducing ligand) is a TNF family member that binds two TNF receptor family members, TACI and BCMA. It shares these receptors with the closely related TNF family member,...
9.
Swers J, Widom A, Phan U, Springer T, Wittrup K
Biochem Biophys Res Commun
. 2006 Oct;
350(3):508-13.
PMID: 17027652
We have characterized the IgG form of a previously isolated and engineered single-chain Fv (scFv), named RR2r3s4-1, that binds to human PSGL-1. This fully human IgG was determined to have...
10.
Salas A, Shimaoka M, Phan U, Kim M, Springer T
J Biol Chem
. 2006 Mar;
281(16):10876-82.
PMID: 16505487
AlphaLbeta2 affinity for intercellular adhesion molecule-1 (ICAM-1) is regulated by the conformation of the alphaL I domain, which is in turn controlled by the conformation and orientation of other adjacent...