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Urania Georgopoulou

Explore the profile of Urania Georgopoulou including associated specialties, affiliations and a list of published articles. Areas
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Articles 37
Citations 453
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Recent Articles
21.
Foka P, Dimitriadis A, Kyratzopoulou E, Giannimaras D, Sarno S, Simos G, et al.
Cell Mol Life Sci . 2014 Apr; 71(21):4243-58. PMID: 24718935
Hepatitis C virus (HCV) infection is associated with hepatic iron overload and elevated serum iron that correlate to poor antiviral responses. Hepcidin (HAMP), a 25-aa cysteine-rich liver-specific peptide, controls iron...
22.
Georgopoulou U, Dimitriadis A, Foka P, Karamichali E, Mamalaki A
Virulence . 2014 Mar; 5(4):465-76. PMID: 24626108
An estimated 30-40% of patients with chronic hepatitis C have elevated serum iron, transferrin saturation, and ferritin levels. Clinical data suggest that iron is a co-morbidity factor for disease progression...
23.
Foka P, Karamichali E, Dalagiorgou G, Serti E, Doumba P, Pissas G, et al.
J Hepatol . 2013 Aug; 60(1):30-8. PMID: 23978712
Background & Aims: HCV relies on host lipid metabolism to complete its life cycle and HCV core is crucial to this interaction. Liver secreted ANGPTL-3 is an LXR- and HNF-1α-regulated...
24.
Doumba P, Serti E, Boutsikou M, Konstadoulakis M, Georgopoulou U, Koskinas J
Cell Mol Life Sci . 2013 May; 70(18):3463-74. PMID: 23645326
Hepatitis C virus non-enveloped particles circulate in the serum of HCV-infected patients and are believed to be involved in viral persistence. It was previously demonstrated that recombinant HCVne particles can...
25.
Dalagiorgou G, Piperi C, Georgopoulou U, Adamopoulos C, Basdra E, Papavassiliou A
Cell Mol Life Sci . 2012 Sep; 70(1):167-180. PMID: 23014991
Mechanical forces trigger biological responses in bone cells that ultimately control osteoblastogenesis and bone program. Although several mechanosensors have been postulated, the precise mechanotransduction pathway remains obscure as the initial...
26.
Katsarou K, Tsitoura P, Georgopoulou U
Biochim Biophys Acta . 2011 Jul; 1813(10):1854-62. PMID: 21767578
Hepatitis C virus (HCV) is an RNA positive strand virus, member of the Flaviviridae family. The viral particle is composed of a capsid containing the genome, surrounded by E1 and...
27.
Budkowska A, Kakkanas A, Nerrienet E, Kalinina O, Maillard P, Horm S, et al.
PLoS One . 2011 Feb; 6(1):e15871. PMID: 21283512
The biological role of the protein encoded by the alternative open reading frame (core+1/ARF) of the Hepatitis C virus (HCV) genome remains elusive, as does the significance of the production...
28.
Boumlic A, Vassilaki N, Dalagiorgou G, Kochlios E, Kakkanas A, Georgopoulou U, et al.
Virus Res . 2010 Oct; 155(1):213-20. PMID: 20959129
The hepatitis C virus possesses an alternative open reading frame overlapping the Core gene, whose products are referred to as Core+1 or alternative reading frame (ARF) or F protein(s). Extensive...
29.
Serti E, Doumba P, Thyphronitis G, Tsitoura P, Katsarou K, Foka P, et al.
Cell Mol Life Sci . 2010 Aug; 68(3):505-22. PMID: 20680391
Hepatitis C virus (HCV) has been shown to actively replicate in cells of the immune system, altering both their function and cytokine expression. Naked nucleocapsids have been reported in the...
30.
Katsarou K, Lavdas A, Tsitoura P, Serti E, Markoulatos P, Mavromara P, et al.
Cell Mol Life Sci . 2010 Apr; 67(14):2491-506. PMID: 20358251
Although HCV is an enveloped virus, naked nucleocapsids have been reported in the serum of infected patients. The HCV core particle serves as a protective capsid shell for the viral...